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Children's Oncology Group

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia

Phase 3

Completed

Conditions: Leukemia

Interventions: Drug: cyclophosphamide
Drug: leucovorin calcium
Drug: cytarabine
Drug: daunorubicin hydrochloride
Drug: mercaptopurine
Drug: dexamethasone
Drug: methotrexate
Drug: vincristine sulfate
Drug: pegaspargase
Drug: thioguanine

First Posted Date: 2003-01-27

Last Posted Date: 2023-04-06

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 1076

Registration Number: NCT00005596

Locations: 🇺🇸
Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Cancer Research Institute, Mobile, Alabama, United States
🇺🇸
Arizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona, United States

and more 119 locations

Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia

Phase 3

Completed

Conditions: Leukemia

Interventions: Drug: dexamethasone
Drug: cyclophosphamide
Drug: leucovorin calcium
Drug: cytarabine
Drug: daunorubicin hydrochloride
Drug: mercaptopurine
Drug: methotrexate
Drug: vincristine sulfate
Drug: pegaspargase
Drug: thioguanine

First Posted Date: 2003-01-27

Last Posted Date: 2023-04-06

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 838

Registration Number: NCT00005585

Locations: 🇺🇸
Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Cancer Research Institute, Mobile, Alabama, United States
🇺🇸
Arizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona, United States

and more 119 locations

Monoclonal Antibody Plus Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes

Phase 1

Completed

Conditions: Leukemia
Myelodysplastic Syndromes

First Posted Date: 2003-01-27

Last Posted Date: 2014-02-20

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 47

Registration Number: NCT00028899

Locations: 🇺🇸
Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 73 locations

Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma

Phase 2

Completed

Conditions: Brain and Central Nervous System Tumors

Interventions: Drug: temozolomide
Procedure: adjuvant therapy
Radiation: radiation therapy

First Posted Date: 2003-01-27

Last Posted Date: 2014-02-21

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 170

Registration Number: NCT00028795

Locations: 🇺🇸
Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Cancer Research Institute, Mobile, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States

and more 226 locations

Gemcitabine in Treating Children With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia

Phase 2

Completed

Conditions: Leukemia

Interventions: Drug: gemcitabine hydrochloride

First Posted Date: 2003-01-27

Last Posted Date: 2014-02-20

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 32

Registration Number: NCT00006462

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Medical Center, Mobile, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States

and more 221 locations

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma

Phase 3

Completed

Conditions: Sarcoma

First Posted Date: 2003-01-27

Last Posted Date: 2014-02-14

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 483

Registration Number: NCT00002995

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Cancer Research Institute, Mobile, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States

and more 229 locations

Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201

Completed

Conditions: Long-term Effects Secondary to Cancer Therapy in Children
Neurotoxicity

First Posted Date: 2003-01-27

Last Posted Date: 2014-02-13

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 66

Registration Number: NCT00028509

Locations: 🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
🇺🇸
Stanford Comprehensive Cancer Center - Stanford, Stanford, California, United States
🇺🇸
University of Miami Sylvester Comprehensive Cancer Center - Miami, Miami, Florida, United States

and more 23 locations

Genetic Study of Children With Soft Tissue Sarcoma or Rhabdomyosarcoma

Completed

Conditions: Sarcoma
Leukemia
Myelodysplastic Syndromes

Interventions: Genetic: microsatellite instability analysis
Genetic: clonality analysis
Genetic: mutation analysis

First Posted Date: 2003-01-27

Last Posted Date: 2014-08-05

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 294

Registration Number: NCT00003793

Locations: 🇺🇸
Southern California Permanente Medical Group, Downey, California, United States
🇺🇸
Jonathan Jaques Children's Cancer Center at Miller Children's Hospital, Long Beach, California, United States
🇺🇸
Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, California, United States

and more 93 locations

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma

Phase 2

Completed

Conditions: Sarcoma

First Posted Date: 2003-01-27

Last Posted Date: 2014-02-14

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 77

Registration Number: NCT00003955

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Cancer Research Institute, Mobile, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States

and more 233 locations

Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia

Phase 2

Completed

Conditions: Leukemia

Interventions: Biological: filgrastim
Drug: asparaginase
Drug: cyclophosphamide
Drug: cytarabine
Drug: daunorubicin hydrochloride
Drug: etoposide
Drug: leucovorin calcium
Drug: mercaptopurine
Drug: methotrexate
Drug: prednisone
Drug: therapeutic hydrocortisone
Drug: vincristine sulfate

First Posted Date: 2003-01-27

Last Posted Date: 2014-02-14

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 221

Registration Number: NCT00002756

Locations: 🇺🇸
Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 137 locations

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