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Children's Oncology Group

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma

Phase 3

Completed

Conditions: Stage 4S Neuroblastoma
Localized Unresectable Neuroblastoma
Regional Neuroblastoma
Stage 4 Neuroblastoma
Localized Resectable Neuroblastoma

Interventions: Other: Clinical Observation
Drug: Cyclophosphamide
Other: Laboratory Biomarker Analysis
Procedure: Magnetic Resonance Imaging
Drug: Prednisone
Biological: Therapeutic Immune Globulin

First Posted Date: 2003-01-27

Last Posted Date: 2023-04-18

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 53

Registration Number: NCT00033293

Locations: 🇺🇸
Children's Hospital of Alabama, Birmingham, Alabama, United States
🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
🇺🇸
Banner University Medical Center - Tucson, Tucson, Arizona, United States

and more 101 locations

Gene Testing to Help in the Diagnosis and Treatment of Childhood Brain Tumors

Completed

Conditions: Brain Tumors
Central Nervous System Tumors

First Posted Date: 2003-01-27

Last Posted Date: 2014-08-06

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 88

Registration Number: NCT00003096

Locations: 🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Southern California Permanente Medical Group, Downey, California, United States
🇺🇸
Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma Linda, California, United States

and more 58 locations

Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors

Phase 2

Completed

Conditions: Brain Tumor
Central Nervous System Tumor

Interventions: Biological: Sargramostim
Drug: cyclophosphamide
Drug: melphalan
Procedure: autologous bone marrow transplantation
Procedure: bone marrow ablation with stem cell support
Procedure: peripheral blood stem cell transplantation

First Posted Date: 2003-01-27

Last Posted Date: 2014-07-24

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 31

Registration Number: NCT00002594

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Medical Center, Mobile, Alabama, United States
🇺🇸
Arizona Cancer Center, Tucson, Arizona, United States

and more 114 locations

STI571 in Treating Patients With Recurrent Leukemia

Phase 1

Completed

Conditions: Leukemia

Interventions: Drug: imatinib mesylate

First Posted Date: 2003-01-27

Last Posted Date: 2014-02-21

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 31

Registration Number: NCT00004932

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Medical Center, Mobile, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States

and more 231 locations

Antibiotic Therapy With or Without G-CSF in Treating Children With Neutropenia and Fever Caused by Chemotherapy

Phase 3

Completed

Conditions: Fever, Sweats, and Hot Flashes
Neutropenia
Unspecified Childhood Solid Tumor, Protocol Specific

First Posted Date: 2003-01-27

Last Posted Date: 2014-02-14

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 67

Registration Number: NCT00003739

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Medical Center, Mobile, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States

and more 231 locations

Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma

Phase 2

Completed

Conditions: Central Nervous System Tumor
Brain Tumor

Interventions: Radiation: radiation therapy
Biological: filgrastim
Drug: carboplatin
Drug: cyclophosphamide
Drug: etoposide
Drug: vincristine sulfate
Drug: Mesna
Procedure: therapeutic conventional surgery

First Posted Date: 2003-01-27

Last Posted Date: 2019-08-07

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 378

Registration Number: NCT00027846

Locations: 🇺🇸
Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 161 locations

Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney Tumors

Phase 3

Completed

Conditions: Kidney Cancer

Interventions: Biological: dactinomycin
Biological: filgrastim
Drug: cyclophosphamide
Drug: carboplatin
Drug: doxorubicin hydrochloride
Procedure: conventional surgery
Drug: etoposide
Drug: vincristine sulfate
Radiation: radiation therapy

First Posted Date: 2003-01-27

Last Posted Date: 2014-07-25

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 203

Registration Number: NCT00002610

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Medical Center, Mobile, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States

and more 231 locations

Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma

Phase 3

Completed

Conditions: Lymphoma

Interventions: Drug: asparaginase
Drug: cyclophosphamide
Drug: cytarabine
Drug: daunorubicin hydrochloride
Drug: dexamethasone
Drug: doxorubicin hydrochloride
Drug: leucovorin calcium
Drug: mercaptopurine
Drug: methotrexate
Drug: prednisone
Drug: thioguanine
Drug: vincristine sulfate
Radiation: radiation therapy

First Posted Date: 2003-01-27

Last Posted Date: 2019-08-06

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 393

Registration Number: NCT00004228

Locations: 🇺🇸
Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 172 locations

Docetaxel in Treating Children With Relapsed or Refractory Acute Lymphoblastic or Acute Myeloid Leukemia

Phase 2

Completed

Conditions: Leukemia

Interventions: Drug: docetaxel

First Posted Date: 2003-01-27

Last Posted Date: 2014-08-08

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 12

Registration Number: NCT00021242

Locations: 🇺🇸
Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Cancer Research Institute, Mobile, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States

and more 224 locations

Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors

Phase 2

Completed

Conditions: Childhood Germ Cell Tumor
Brain Tumor
Central Nervous System Tumors

Interventions: Drug: carboplatin
Drug: etoposide
Drug: ifosfamide
Drug: thiotepa
Procedure: adjuvant therapy
Procedure: conventional surgery
Procedure: neoadjuvant therapy
Procedure: peripheral blood stem cell transplantation
Radiation: radiation therapy

First Posted Date: 2003-01-27

Last Posted Date: 2018-02-14

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 104

Registration Number: NCT00047320

Locations: 🇺🇸
Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 102 locations

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