Children's Oncology Group

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant

Phase 3

Completed

Conditions: Bacterial Infection
Methicillin-Resistant Staphylococcus Aureus Infection
Benign Neoplasm
Myeloid Neoplasm
Recurrent Childhood Acute Myeloid Leukemia
Malignant Neoplasm
Recurrent Childhood Acute Lymphoblastic Leukemia

Interventions: Procedure: Chlorhexidine Gluconate Skin Cleanser
Other: Laboratory Biomarker Analysis
Procedure: Mild Soap Skin Cleanser
Other: Questionnaire Administration

First Posted Date: 2013-03-22

Last Posted Date: 2021-06-22

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 177

Registration Number: NCT01817075

Locations: 🇺🇸
Valley Children's Hospital, Madera, California, United States
🇺🇸
Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia, United States
🇺🇸
Eastern Maine Medical Center, Bangor, Maine, United States

and more 56 locations

Gene Analysis in Studying Susceptibility to Wilms Tumor

Completed

Conditions: Stage II Kidney Wilms Tumor
Stage III Kidney Wilms Tumor
Stage IV Kidney Wilms Tumor
Recurrent Childhood Kidney Neoplasm
Stage I Kidney Wilms Tumor

Interventions: Other: Laboratory Biomarker Analysis

First Posted Date: 2013-03-11

Last Posted Date: 2016-08-22

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 1

Registration Number: NCT01808079

Locations: 🇺🇸
Childrens Oncology Group, Philadelphia, Pennsylvania, United States

Genetic Biomarkers in Tissue Samples From Patients With Osteosarcoma

Completed

Conditions: Osteosarcoma

Interventions: Other: laboratory biomarker analysis

First Posted Date: 2013-03-08

Last Posted Date: 2016-03-08

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 10

Registration Number: NCT01807143

Locations: 🇺🇸
Children's Oncology Group, Monrovia, California, United States

Biomarker Expression in Tissue Samples From Patients With Bone Sarcomas

Completed

Conditions: Localized Osteosarcoma
Metastatic Osteosarcoma
Recurrent Osteosarcoma

Interventions: Other: laboratory biomarker analysis

First Posted Date: 2013-03-08

Last Posted Date: 2016-05-19

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 34

Registration Number: NCT01807052

Locations: 🇺🇸
Children's Oncology Group, Monrovia, California, United States

Biomarker Differences in Samples From Patients With Undifferentiated Sarcomas

Completed

Conditions: Soft Tissue Sarcoma

Interventions: Other: laboratory biomarker analysis

First Posted Date: 2013-03-01

Last Posted Date: 2016-07-14

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 49

Registration Number: NCT01802125

Locations: 🇺🇸
Children's Oncology Group, Monrovia, California, United States

Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Phase 1

Completed

Conditions: Stage 2B Neuroblastoma
Stage 4S Neuroblastoma
Stage 1 Neuroblastoma
Stage 4 Neuroblastoma
Stage 2 Neuroblastoma
Ganglioneuroblastoma
Stage 2A Neuroblastoma
Stage 3 Neuroblastoma

Interventions: Procedure: Autologous Hematopoietic Stem Cell Transplantation
Drug: Busulfan
Drug: Cisplatin
Drug: Cyclophosphamide
Drug: Doxorubicin Hydrochloride
Drug: Etoposide
Radiation: External Beam Radiation Therapy
Biological: Filgrastim
Other: Laboratory Biomarker Analysis
Drug: Melphalan
Drug: Mesna
Procedure: Peripheral Blood Stem Cell Transplantation
Other: Pharmacological Study
Drug: Topotecan Hydrochloride
Drug: Vincristine Sulfate

First Posted Date: 2013-02-25

Last Posted Date: 2024-07-15

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 150

Registration Number: NCT01798004

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
🇨🇦
Hospital for Sick Children, Toronto, Ontario, Canada
🇺🇸
Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida, United States

and more 120 locations

Blood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed Lymphomas

Completed

Conditions: Burkitt Lymphoma
Hodgkin Lymphoma
Lymphoma
Anaplastic Large Cell Lymphoma
Diffuse Large B-Cell Lymphoma

Interventions: Other: Laboratory Biomarker Analysis
Other: Questionnaire Administration

First Posted Date: 2013-02-15

Last Posted Date: 2024-08-26

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 203

Registration Number: NCT01793233

Locations: 🇺🇸
Seattle Children's Hospital, Seattle, Washington, United States
🇺🇸
Methodist Children's Hospital of South Texas, San Antonio, Texas, United States
🇺🇸
University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

and more 104 locations

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

Recruiting

Conditions: Osteosarcoma
Recurrent Leukemia
Lymphoblastic Lymphoma
Hodgkin Lymphoma in Remission
Leukemia in Remission
Recurrent Lymphoma
Recurrent Malignant Neoplasm

Interventions: Other: Assessment of Therapy Complications
Other: Laboratory Biomarker Analysis
Other: Quality-of-Life Assessment
Other: Questionnaire Administration

First Posted Date: 2013-02-13

Last Posted Date: 2024-04-17

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 420

Registration Number: NCT01790152

Locations: 🇺🇸
Sinai Hospital of Baltimore, Baltimore, Maryland, United States
🇺🇸
Hurley Medical Center, Flint, Michigan, United States
🇺🇸
Columbia Regional, Columbia, Missouri, United States

and more 76 locations

Biomarkers in Patients With Advanced Rhabdomyosarcoma

Completed

Conditions: Childhood Embryonal Rhabdomyosarcoma
Recurrent Adult Soft Tissue Sarcoma
Stage III Adult Soft Tissue Sarcoma
Childhood Alveolar Rhabdomyosarcoma
Previously Treated Childhood Rhabdomyosarcoma
Recurrent Childhood Rhabdomyosarcoma
Stage IV Adult Soft Tissue Sarcoma
Adult Rhabdomyosarcoma