To compare pressure controlled ventilation with volume controlled ventilation during one lung ventilation during surgery

Phase 3

• Conditions: Intraoperative Thoracic surgery

• Registration Number: CTRI/2010/091/000573

Brief Summary

The use of pressure control ventilation with PEEP during one lung ventilation is found to be associated with significantly lower peak airway pressures as compared to volume control ventilation with PEEP. However pressure control ventilation with PEEP did not result in improvement in arterial oxygenation.

Detailed Description

Not available

Recruitment & Eligibility

• Sex: Not specified
• Target Recruitment: 32

Inclusion Criteria

Adult patients ASA physical status II-III undergoing elective open thoracotomy in lateral position requiring one lung anaesthesia for at least one hour.

Exclusion Criteria

Patients with history of severe cardiovascular, hepatic or renal disease.

Study & Design

• Study Type: Not specified
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Peak inspiratory pressure (P peak), mean inspiratory pressure (P mean), plateau inspiratory pressure (P plateau), arterial PaO2,were recorded	(1)During two-lung ventilation using VCV before initiation of OLV (VCV- ZEEP)(2) During OLV 20 mins after the first randomized ventilation mode (3) 20 mins after the second ventilation mode

Secondary Outcome Measures

Name	Time	Method
PaCO2, pH,arterial blood pressure, and expired TV	(1)During two-lung ventilation using VCV before initiation of OLV (VCV- ZEEP)(2) During OLV 20 mins after the first randomized ventilation mode (3) 20 mins after the second ventilation mode

Trial Locations

Locations (1)

Department Of Anaesthesiology, AIIMS, NEW DELHI; 🇮🇳 India

Department Of Anaesthesiology, AIIMS, NEW DELHI

🇮🇳India

Dr.Avneep Aggarwal

Principal investigator

09780988126

avn.aiims@gmail.com