Breaking up prolonged sitting with intermittent standing: acute effects in overweight inactive adults.
- Conditions
- Type 2 diabetesOverweight and obesityMetabolic and Endocrine - DiabetesDiet and Nutrition - Obesity
- Registration Number
- ACTRN12612000664842
- Lead Sponsor
- Baker IDI Heart and Diabetes Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 50
Inclusion criteria includes: overweight or obesity (body mass index greater than or equal to 25kg/m2 but less than or equal to 45kg/m2) and English speaking
Exclusion is based on: of pregnancy; employment in a non-sedentary occupation (< 5 hours total sitting during the typical workday); currently watching < 3 hours of total screen (including television, computer or electronic games) time per day; regularly engaged in moderate-vigorous physical activity greater than or equal to 150min/week > 3 months; use of carbohydrate or lipid-lowering medication; greater than or equal to 5 previous vasovagal syncope episodes or epilepsy; known physical activity contraindications; major illness/injury (acute or chronic), smokers; orthostatic intolerance, and the use of aspirin or other anticoagulants.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postprandial plasma insulin levels (mean AUC). Plasma insulin concentrations will be assessed using standard testing equipment at an outsourced medical laboratory.[Blood insulin levels will be measured every hour for determination of the mean AUC. The mean AUC will be determined at day 7 and day 14 following study enrolment.];Postprandial plasma glucose levels (mean area under the curve [AUC]). Plasma glucose concentrations will be assessed using standard testing equipment at an outsourced medical laboratory.[Blood glucose levels will be measured every hour for determination of the mean AUC. The mean AUC will be determined at day 7 and day 14 following study enrolment.]
- Secondary Outcome Measures
Name Time Method