Taking regular breaks from sitting to improve blood glucose control and blood vessel health in type 1 diabetes

Not Applicable

• Conditions: Type 1 diabetes; Metabolic and Endocrine - Diabetes; Cardiovascular - Hypertension

• Registration Number: ACTRN12618000126213
• Lead Sponsor: Professor David Dunstan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-01-30
• Last Update Posted: 10 March 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

Eligibility will be based on: age (25-65 years), HbA1c (less than or equal to 10%), clinical diagnosis of type 1 diabetes for more than or equal to 12 months, and treatment with insulin pump therapy for more than or equal to 6 months, with pump settings reviewed by a health professional in the previous 3 months.

Exclusion Criteria

Exclusion will be based on: use of glucose-lowering agents other than insulin (e.g. metformin, GLP1 agonist); clinical history of delayed gastric emptying; having experienced a severe hypoglycaemic episode (requiring assistance) within the last 3 months; BMI <20 or >30 kg/m2; highly active (moderate intensity physical activity >300 min/wk); severe vascular complications or other conditions limiting the ability to comply with study protocols (e.g. renal impairment eGFR <60; major cardiovascular or cerebrovascular event in the previous 12 months; hospitalisation due to diabetic ketoacidosis in the previous month); fasting C-peptide greater than or equal to 50 pmol/L; current smoker; and pregnancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified