Glucose lowering effect Of walking breaks in pregnancy study

Not Applicable

Recruiting

• Conditions: Gestational Diabetes Mellitus; Metabolic and Endocrine - Diabetes; Reproductive Health and Childbirth - Fetal medicine and complications of pregnancy

• Registration Number: ACTRN12616000945426
• Lead Sponsor: Professor David Dunstan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-07-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 25

Inclusion Criteria

Eligibility includes women 24-28 weeks gestation and at increased risk for developing gestational diabetes mellitus identified by a validated risk prediction tool (Monash GDM score greater than 4).

Exclusion Criteria

Exclusion will be based on: less than 18 years of age, multiple pregnancy, diagnosed type 1 or 2 diabetes, a BMI greater than 45 kg/m^2, pre-existing chronic medical conditions, absolute contraindications to aerobic exercise during pregnancy according to the American College of Obstetricians and Gynecologists (ACOG) guidelines, currently sitting for less than 5 hours per day, regularly engaged in moderate-intensity exercise more than 150 min/week for more than 3 months, current smoker or use of nicotine replacement therapy, and non-English speaking.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postprandial glycaemic response calculated as mean area under the curve (AUC) from half hourly venous blood sampling over two 4.5 hour experimental conditions <br>[Blood samples for assessment of plasma glucose will be collected half-hourly until the end of the 4.5 hr period during each experimental conditions <br>]

Secondary Outcome Measures

Name	Time	Method
Postprandial insulin response calculated as mean area under the curve (AUC) from half hourly venous blood sampling over two 4.5 hour experimental conditions [Blood samples for assessment of plasma insulin will be collected half-hourly until the end of the 4.5 hr period during each experimental conditions <br>];Changes in resting blood pressure using automated oscillometric blood pressure monitor[In each experimental condition, blood pressure will be measured every hour in a resting state ]