Resistance Training in the Fasted State

Not Applicable

Completed

• Conditions: Fasting; Resistance Training; Exercise
• Interventions: Other: Resistance training in the fasted state; Other: Resistance training in the fed state

• Registration Number: NCT05482750
• Lead Sponsor: Federal University of Rio Grande do Sul

Brief Summary

It is well evidenced in the literature that fasting aerobic exercise generates a series of metabolic differences when compared to exercise performed in the fed state, including the use of fats predominantly as an energy source. Consequently, increases in adaptations to aerobic training, related to health and physical performance, are observed when sessions are performed in the fasted state. In relation to resistance training, the evidence is limited. There is a lack of data in the literature regarding the effects of fasting on resistance exercises and whether this practice may reflect in losses or improvements in morphological and neuromuscular adaptations related to resistance training. Thus, the aim of the present project is to compare the effects of resistance training performed in the fasted state compared to the fed state during 12 weeks on body composition and physical performance in young adults. Thirty-four eutrophic or overweight individuals, not engaged in regular resistance exercises, aged between 20 and 40 years, will be recruited. They will be put on a standard customized diet and will perform 2 weekly sessions of resistance exercise after overnight fasting (10 to 12 hours) or in the fed state, for 12 weeks. Before, in the middle and after this period, evaluations of body composition, muscle thickness and quality, maximum dynamic strength and maximum power will be analyzed. Comparisons will be performed using Generalized Estimating Equations (GEE), adopting the factors group (2 stratifications) and time (3 stratifications). All results will be expressed as mean and standard deviation and the accepted significance level will be 5%.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-23
• Study First Submitted: 2022-07-25
• Study First Submitted QC: 2022-07-28
• Study First Posted: 2022-08-01
• Primary Completion: 2022-12-23
• Study Completion: 2022-12-23
• Status Verified: 2023-05
• Last Update Submitted: 2023-05-08
• Last Update Posted: 2023-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

• Men and women;
• Aged between 19 and 40 years;
• Body mass index (BMI) between 18 and 29.9 kg/m²;
• Not engaged in regular strength physical exercise (>1 weekly session) for the last 3 months.

Exclusion Criteria

• Smokers;
• Use of medications and/or supplements that may influence the outcomes evaluated;
• Individuals who have a chronic disease that may prevent physical exercise.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Resistance training in the fasted state	Resistance training in the fasted state	Subjects will maintain the standard diet and will perform resistance exercise sessions after overnight fasting (10 to 12 hours). Over the 12 weeks of intervention, participants will perform two sessions a week of resistance exercises.
Resistance training in the fed state	Resistance training in the fed state	Subjects will maintain the standard diet and will perform resistance exercise sessions in the fed state, between 1 and 2 hours after consuming a carbohydrate-containing meal. Over the 12 weeks of intervention, participants will perform two sessions a week of resistance exercises.

Primary Outcome Measures

Name	Time	Method
Lean body mass	15 minutes	Lean body mass will be determined using the dual energy X-ray absorption (DEXA) method, using a densitometry machine (Hologic GE, Bedford, USA).
Muscle quality	30 minutes	Muscle quality will be evaluated through echo intensity of the quadriceps through ultrasound (Nemio XG, Toshiba, Japan).
Body mass	1 minute	Body mass will be measured using a scale (Urano, Canoas, Brazil).
Maximum dynamic strength	30 minutes	Maximum dynamic strength will be assessed using the 1 repetition maximum (1RM) test for bench press and knee extension exercises.
Maximum power	30 minutes	The maximum power and the medium power will be evaluated in the bench press and knee extension exercises considering a load of 30 and 70% of 1RM.
Fat body mass	15 minutes	Fat body mass will be determined using the dual energy X-ray absorption (DEXA) method, using a densitometry machine (Hologic GE, Bedford, USA).
Muscle thickness	30 minutes	Muscle thickness will be evaluated through ultrasound (Nemio XG, Toshiba, Japan).

Trial Locations

Locations (1)

Escola de Educação Física, Fisioterapia e Dança - UFRGS; 🇧🇷 Porto Alegre, Rio Grande Do Sul, Brazil