Preadministration of 6 percent Hydroxy ethyl starch before induction with propofol for reduction of pain on propofol injection.
Not yet recruiting
- Conditions
- Administration, ,
- Registration Number
- CTRI/2024/05/067424
- Lead Sponsor
- Department of anaesthesiology SMS medical college jaipur
- Brief Summary
Propofol is most widely used intravenous agent for induction of anaesthesia. The immediate pain is due to irritation of vein and delayed pain is due to kin in release on propofol injection. Colloids have the capacity to modify endothelial cell junctions and permeability of the vascular endothelium by various substances and molecules.With this background we plan to conduct this study to compare the effect of pre-administration of 6% hydroxy ethyl starch for reduction of pain on propofol injection.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 130
Inclusion Criteria
- Patients undergoing elective surgery under general anaesthesia.
- Patients willing to give written informed consent.
- ASA grade 1 and 2.
Exclusion Criteria
- Patients with history of allergy to propofol or hydroxy ethyl starch Patients with pre-existing renal or hepatic dysfunction.
- Patients with cardiovascular disease,hypertension,diabetes.
- Emergency surgeries.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence of pain on propofol injection between the study groups 0 second 10 second. 20 second. before loss of verbal contact
- Secondary Outcome Measures
Name Time Method To compare the severity of pain on propofol injection between the study groups 0 second. 10 second. 20 second. before loss of verbal contact
Trial Locations
- Locations (1)
SMS medical college and attached hospitals.
🇮🇳Jaipur, RAJASTHAN, India
SMS medical college and attached hospitals.🇮🇳Jaipur, RAJASTHAN, IndiaMamta SharmaPrincipal investigator7733019098dr.mamtasharma18@gamil.com