Effect of intra-operative sedation with low-doses of S-Ketamine on depression in the elderly: randomized double-blind controlled trial

Phase 2

Completed

• Conditions: Mental Depression; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12610001090000
• Lead Sponsor: Margarida Castanheira Rodrigues Bretas Bastos, MD

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-12-13
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

age>60, males and females;spinal or epidural anaesthesia; patients with depression criteria according to Diagnostic and Statistical Manual of Mental Disorders; patients without depression (control).

Exclusion Criteria

patients with depression, but that scored < 7 (Hamilton Scale) ;
- arterial hypertension not correctly treated; -unstable angina; severe cardiovascular disease; anaemia (<10 g.dl ; hyper or hypothyroidism not correctly treated; morbid obesity; -convulsive episodes; - schizophrenia; -psychotic disorders; -drug addiction; -patients that used the last 15 days monoamine oxidase inhibitors and lithium

Study & Design

• Study Type: Interventional
• Study Design: Not specified