The use of Ketamine as an anaesthetic during electroconvulsive therapy (ECT) for depression: does it improve treatment outcome? - The use of Ketamine as an anaesthetic during electroconvulsive therapy

Phase 1

• Conditions: Depression.; MedDRA version: 13.1 Level: PT Classification code 10014404 Term: Electroconvulsive therapy System Organ Class: 10042613 - Surgical and medical procedures; MedDRA version: 13.1 Level: SOC Classification code 10037175 Term: Psychiatric disorders System Organ Class: 10037175 - Psychiatric disorders; MedDRA version: 13.1 Level: LLT Classification code 10012384 Term: Depression endogenous System Organ Class: 10037175 - Psychiatric disorders

• Registration Number: EUCTR2011-000396-14-GB
• Lead Sponsor: niversity of Aberdeen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-04-12
• Study Completion: 2014-02-18
• Last Update Posted: 30 June 2019

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

- Between the ages of 18 and 75. - Diagnosed with depression and being referred for ECT. - American Society of Anesthesiologists (ASA) score of 1 or 2. - Patient receiving ECT on an informal basis (i.e. consenting to treatment and able to give informed consent).
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

- pre-existing neurological disease or cognitive impairment - co-morbid psychiatric diagnoses - pre-existing severe hypertension - severe respiratory tract disease - major cardiovascular disease - pacemakers - significant cerebrovascular disorder or malformation - intracranial mass lesions - seizure disorder - intracranial electrode and clips - severe intra-ocular pathology - significant endocrine or metabolic disease - severe hematologic disease - severe fracture - not able to give consent - pregnancy - obesity

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified