Esomeprazole
- Generic Name
- Esomeprazole
- Brand Names
- Nexium, Vimovo, Nexium Control
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19N3O3S
- CAS Number
- 119141-88-7
- Unique Ingredient Identifier
- N3PA6559FT
- Background
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison ...
- Indication
Esomeprazole is indicated for the treatment of acid-reflux disorders including healing and maintenance of erosive esophagitis, and symptomatic gastroesophageal reflux disease (GERD), peptic ulcer disease, H. pylori eradication, prevention of gastrointestinal bleeds with NSAID use, and for the long-term treatment of pathological hypersecretory conditions incl...
- Associated Conditions
- Duodenal Ulcer, Erosive Esophagitis, Gastro-esophageal Reflux Disease (GERD), Heartburn, Helicobacter Pylori Infection, Stress Ulcers, Upper Gastrointestinal Hemorrhage, Zollinger-Ellison Syndrome, Acute benign gastric ulcers, Develop NSAID-induced gastric ulcers, Maintenance of healing Erosive esophagitis, Postendoscopy Bleeding
- Associated Therapies
- -
A Study to Assess the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics (PK) of TAK-931 in Participants With Advanced Solid Tumors
- Conditions
- Interventions
- First Posted Date
- 2018-10-17
- Last Posted Date
- 2020-12-29
- Lead Sponsor
- Millennium Pharmaceuticals, Inc.
- Target Recruit Count
- 20
- Registration Number
- NCT03708211
- Locations
- 🇳🇱
Leiden University Medical Center, Department of Clinical Oncology, Leiden, Zuid-holland, Netherlands
🇳🇱Erasmus MC Cancer Institute, Department of Internal Oncology, Rotterdam, Zuid-holland, Netherlands
🇳🇱Radboud University Medical Center, Department of Medical Oncology, Nijmegen, Gelderland, Netherlands
Tailored Therapy for Helicobacter Pylori Treatment in Patients With Penicillin Allergy
- Conditions
- Interventions
- First Posted Date
- 2018-10-17
- Last Posted Date
- 2019-12-10
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 112
- Registration Number
- NCT03708848
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
Evaluation of Saccharomyces Boulardii Combined With Standard Quadruple Therapy for Eradication of Helicobacter Pylori
- Conditions
- Interventions
- First Posted Date
- 2018-09-28
- Last Posted Date
- 2021-10-26
- Lead Sponsor
- Huazhong University of Science and Technology
- Target Recruit Count
- 360
- Registration Number
- NCT03688828
- Locations
- 🇨🇳
Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, Hubei, China
Helicobacter Rescue Therapy With Berberine Plus Amoxicillin Quadruple Therapy Versus Tetracycline Plus Furazolidone Quadruple Therapy
- First Posted Date
- 2018-08-01
- Last Posted Date
- 2019-08-30
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 658
- Registration Number
- NCT03609892
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xi'an, Shaanxi, China
PK/PD Clinical Trial of YYD601 in Healthy Adult Male
- First Posted Date
- 2018-06-15
- Last Posted Date
- 2018-06-15
- Lead Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
- Target Recruit Count
- 30
- Registration Number
- NCT03558477
- Locations
- 🇰🇷
Kyungpook national university hospital, Daegu, Korea, Republic of
High Dose of Amoxicillin and Metronidazole Plus Bismuth For Helicobacter Pylori Treatment
- Conditions
- Interventions
- First Posted Date
- 2018-06-15
- Last Posted Date
- 2019-06-18
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 216
- Registration Number
- NCT03557437
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery
- Conditions
- Interventions
- First Posted Date
- 2018-04-04
- Last Posted Date
- 2020-11-23
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Registration Number
- NCT03488147
- Locations
- 🇺🇸
Mount Sinai West, New York, New York, United States
🇺🇸Icahn School of Medicine at Mount Sinai, New York, New York, United States
Esomeprazole to Reduce Organ Failure in Sepsis
- First Posted Date
- 2018-03-02
- Last Posted Date
- 2024-01-19
- Lead Sponsor
- Università Vita-Salute San Raffaele
- Target Recruit Count
- 300
- Registration Number
- NCT03452865
- Locations
- 🇮🇹
Policlinico Univeristario Campus Bio-Medico, Roma, Lazio, Italy
🇮🇹IRCCS San Martino Istitute, Genova, Liguria, Italy
🇮🇹Humanitas Clinical Institute, Rozzano, Lombardy, Italy
Safety Trial of Herbal Melanin in Gastritis Patients
- Conditions
- Interventions
- First Posted Date
- 2018-02-09
- Last Posted Date
- 2018-02-09
- Target Recruit Count
- 132
- Registration Number
- NCT03428568
Tailored Therapy for Helicobacter Pylori Rescue Treatment
- Conditions
- Interventions
- First Posted Date
- 2018-01-29
- Last Posted Date
- 2018-08-07
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 200
- Registration Number
- NCT03413020
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.