Naproxen
- Generic Name
- Naproxen
- Brand Names
- Aleve, Aleve PM, Aleve-D, Anaprox, Naprelan, Naprosyn, Sallus, Sudafed Sinus & Pain, Treximet, Vimovo
- Drug Type
- Small Molecule
- Chemical Formula
- C14H14O3
- CAS Number
- 22204-53-1
- Unique Ingredient Identifier
- 57Y76R9ATQ
- Background
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its overall tolerability and effectiveness, nap...
- Indication
Naproxen is indicated for the management of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and for the relief of mild to moderate pain. Further, it is first-line therapy for osteoarthritis, acute gouty arthritis, dysmenorrhea, and musculoskelet...
- Associated Conditions
- Acute Gouty Arthritis, Acute Migraine, Ankylosing Spondylitis (AS), Back pain, Bursitis, Extra-Articular Rheumatism, Fever, Flu caused by Influenza, Headache, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Muscle Spasms, Nasal Congestion, Osteoarthritis (OA), Pain, Post Traumatic Pain, Postoperative pain, Primary Dysmenorrhoea, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Seasonal Allergic Rhinitis, Sinusitis, Tendinitis, Toothache, Articular inflammation
- Associated Therapies
- -
The Effect of Turmeric on New Onset Primary Dysmenorrhea
- Conditions
- Interventions
- First Posted Date
- 2019-12-03
- Last Posted Date
- 2020-04-24
- Lead Sponsor
- Batman Training and Research Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT04183556
- Locations
- 🇹🇷
Batman Maternity and Child's health Hospital, Batman, Turkey
Mechanistic Characterization of Uterine Pain
- Conditions
- Interventions
- First Posted Date
- 2019-10-30
- Last Posted Date
- 2023-07-20
- Lead Sponsor
- NorthShore University HealthSystem
- Target Recruit Count
- 214
- Registration Number
- NCT04145518
- Locations
- 🇺🇸
NorthShore University HealthSystem, Evanston, Illinois, United States
Individualizing Anti-Inflammatory Medications for Adults With Axial Spondyloarthritis: A Series of N-of 1 Trials
- Conditions
- Interventions
- First Posted Date
- 2019-10-03
- Last Posted Date
- 2023-12-05
- Target Recruit Count
- 42
- Registration Number
- NCT04115098
- Locations
- 🇺🇸
The University of Texas Health Science Center at Houston, Houston, Texas, United States
Symptomatic Management of Lyme Arthritis
- Conditions
- Interventions
- First Posted Date
- 2019-07-30
- Last Posted Date
- 2023-12-05
- Lead Sponsor
- Desiree Neville, MD
- Target Recruit Count
- 300
- Registration Number
- NCT04038346
- Locations
- 🇺🇸
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States
Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS
- Conditions
- Interventions
- First Posted Date
- 2019-07-11
- Last Posted Date
- 2023-03-27
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 70
- Registration Number
- NCT04015596
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Study to Evaluate Arthroplasty Specimens for Osteoarthritis of the Knee and Hip
- Conditions
- Interventions
- First Posted Date
- 2019-05-14
- Last Posted Date
- 2023-10-17
- Lead Sponsor
- Regeneron Pharmaceuticals
- Target Recruit Count
- 23
- Registration Number
- NCT03949673
- Locations
- 🇵🇱
Regeneron Recruting SIte, Bialystok, Poland
🇬🇧Regeneron Research Site, Liverpool, United Kingdom
Inflammation and Daily Life Study
- First Posted Date
- 2018-12-11
- Last Posted Date
- 2024-05-01
- Lead Sponsor
- University of California, Los Angeles
- Target Recruit Count
- 70
- Registration Number
- NCT03771612
- Locations
- 🇺🇸
UCLA Department of Psychology, Los Angeles, California, United States
Examining the Role of Improved NSAID Management in Treating Dysmenorrhea and Bladder Pain
- First Posted Date
- 2018-10-05
- Last Posted Date
- 2023-10-18
- Lead Sponsor
- NorthShore University HealthSystem
- Target Recruit Count
- 26
- Registration Number
- NCT03697720
- Locations
- 🇺🇸
NorthShore University Health System, Evanston, Illinois, United States
A Study to Evaluate the Efficacy and Safety of Gefapixant (MK-7264) in Women With Endometriosis-Related Pain (MK-7264-034)
- Conditions
- Interventions
- First Posted Date
- 2018-08-31
- Last Posted Date
- 2024-11-04
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 187
- Registration Number
- NCT03654326
- Locations
- 🇺🇸
Synexus US Phoenix Southeast ( Site 0729), Chandler, Arizona, United States
🇺🇸Lynn Institute of the Ozarks ( Site 0720), Little Rock, Arkansas, United States
🇺🇸Thameside OBGYN Center ( Site 0747), Groton, Connecticut, United States
MAST Trial: Multi-modal Analgesic Strategies in Trauma
- First Posted Date
- 2018-03-21
- Last Posted Date
- 2021-06-18
- Target Recruit Count
- 1561
- Registration Number
- NCT03472469
- Locations
- 🇺🇸
The University of Texas Health Science Center at Houston, Houston, Texas, United States
Drug Development Updates
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