Sevoflurane

Generic Name
Sevoflurane
Brand Names
Sevorane, Sojourn, Ultane
Drug Type
Small Molecule
Chemical Formula
C4H3F7O
CAS Number
28523-86-6
Unique Ingredient Identifier
38LVP0K73A
Background

Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996. Sevoflurane is three times more potent than desflurane, but has lower potency compared to halothane and isoflurane. Unlike other volatile anesthetics, sevoflurane has a pleasant odor and does not irritate the airway. The hemodynamic and respiratory depressive effects of sevoflurane are well tolerated, and most patients receiving this anesthetic agent present little toxicity. Therefore, it can be used for inhalational induction in adults and children for a wide variety of anesthetic procedures.

Indication

Sevoflurane is used for the induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.

Associated Conditions
-
Associated Therapies
General Anesthesia, Induction and Maintenance of General Anesthesia

Nephrogenic Diabetes Insipidus During Prolonged Sevoflurane Sedation in the ICU: a Retrospective Analysis

Completed
Conditions
Interventions
First Posted Date
2021-06-25
Last Posted Date
2023-04-27
Lead Sponsor
Universitair Ziekenhuis Brussel
Target Recruit Count
1000
Registration Number
NCT04939753
Locations
🇧🇪

UZ Brussel, Jette, Brussel, Belgium

Induction Agent and Incidence of Hypotension in Heart Failure Patients Undergoing LVAD-Implantation

First Posted Date
2021-06-22
Last Posted Date
2021-10-19
Lead Sponsor
Heidelberg University
Target Recruit Count
50
Registration Number
NCT04934410

Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair

First Posted Date
2021-04-29
Last Posted Date
2021-10-26
Lead Sponsor
Heidelberg University
Target Recruit Count
57
Registration Number
NCT04865614
Locations
🇩🇪

Anästhesiologische Klinik (Universitätsklinikum Heidelberg), Heidelberg, Baden-Würtemberg, Germany

The Impact of Inhalation vs Total Intravenous Anesthesia on the Immune Status and Mortality in Patients Undergoing Breast Cancer Surgery: a Prospective Double-Blind Randomized Clinical Trial.

Not Applicable
Recruiting
Conditions
Interventions
First Posted Date
2021-03-16
Last Posted Date
2023-04-26
Lead Sponsor
Moscow Clinical Scientific Center
Target Recruit Count
130
Registration Number
NCT04800393
Locations
🇷🇺

Moscow Scientific Clinical Center, Moscow, Russian Federation

Desflurane and Sevoflurane in Pediatrics With Elevated Liver Enzymes

Not Applicable
Conditions
Interventions
First Posted Date
2021-03-01
Last Posted Date
2021-10-05
Lead Sponsor
National Cancer Institute, Egypt
Target Recruit Count
60
Registration Number
NCT04775212
Locations
🇪🇬

National cancer institute, Cairo, Egypt

The Effect of Anesthesia on Cerebral Oxygenation

First Posted Date
2021-02-18
Last Posted Date
2021-02-18
Lead Sponsor
Karadeniz Technical University
Target Recruit Count
30
Registration Number
NCT04760262
Locations
🇹🇷

Karadeniz Technical University, Trabzon, Turkey

Effects of Intravenous Anesthesia and Balanced Anesthesia on Flash Visual Evoked Potentials

Not Applicable
Recruiting
Conditions
Interventions
First Posted Date
2021-01-26
Last Posted Date
2024-02-06
Lead Sponsor
Beijing Tiantan Hospital
Target Recruit Count
84
Registration Number
NCT04725032
Locations
🇨🇳

Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China

Incidence of Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery

First Posted Date
2021-01-13
Last Posted Date
2024-12-02
Lead Sponsor
Sir Ganga Ram Hospital
Target Recruit Count
270
Registration Number
NCT04707794
Locations
🇮🇳

Sir Ganga Ram Hospital, New Delhi, India

An Evaluation of Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision

First Posted Date
2020-11-30
Last Posted Date
2024-08-02
Lead Sponsor
Alberta Children's Hospital
Target Recruit Count
100
Registration Number
NCT04646967
Locations
🇨🇦

Alberta Children's Hospital, Calgary, Alberta, Canada

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