Remifentanil

Generic Name
Remifentanil
Brand Names
Ultiva
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5
CAS Number
132875-61-7
Unique Ingredient Identifier
P10582JYYK
Background

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

Indication

For use during the induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Immediate postoperative analgesia therapy, Induction and Maintenance of General Anesthesia, Monitored anesthesia care sedation
Clinical Trials
Related News

A Comparison of the Perioperative Hemodynamic Effects of Remifentanil and Esmolol in Intracranial Surgery

First Posted Date
2012-06-27
Last Posted Date
2015-02-18
Lead Sponsor
Diskapi Teaching and Research Hospital
Target Recruit Count
40
Registration Number
NCT01628562
Locations
🇹🇷

Diskapi Yildirim Beyazit Teaching and Research Hospital, Ankara, Turkey

Effect of Remifentanil on Postoperative Cognition Function in Patients Undergoing Major Abdominal Surgery

First Posted Date
2012-06-26
Last Posted Date
2012-06-26
Lead Sponsor
Catholic University of the Sacred Heart
Target Recruit Count
622
Registration Number
NCT01627873
Locations
🇮🇹

Policlinico Universitario "A.Gemelli", Rome, Italy

Patient-controlled Intravenous Analgesia With Remifentanil Infusion for Labour

Not Applicable
Terminated
Conditions
Pain
Interventions
Drug: Remifentanil
First Posted Date
2012-03-27
Last Posted Date
2015-09-04
Lead Sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Target Recruit Count
2
Registration Number
NCT01563939
Locations
🇨🇦

Mount Sinai Hospital, Toronto, Ontario, Canada

Pharmacogenetics of Remifentanil in Patients With Hypertension Undergoing Cesarean Delivery Under General Anesthesia

Not Applicable
Completed
Conditions
Pregnancy
Cesarean Delivery
General Anesthesia
Interventions
Drug: Remifentanil
First Posted Date
2012-03-12
Last Posted Date
2014-11-18
Lead Sponsor
Charles University, Czech Republic
Target Recruit Count
149
Registration Number
NCT01550640
Locations
🇨🇿

General University Hospital in Prague, Prague, Czech Republic

Comparison of Dexmedetomidine and Propofol-Remifentanil Conscious Sedation for Awake Craniotomy for Tumor Surgery

Not Applicable
Completed
Conditions
Brain Tumor
Interventions
Drug: Dexmedetomidine
Drug: Propofol
Drug: Remifentanil
First Posted Date
2012-03-06
Last Posted Date
2016-07-07
Lead Sponsor
Nicolai Goettel
Target Recruit Count
50
Registration Number
NCT01545297
Locations
🇨🇦

UHN Toronto Western Hospital, Toronto, Ontario, Canada

The EC50 of Remifentanil Blunting Hemodynamic Response to Double Lumen Tube Intubation

Not Applicable
Completed
Conditions
Hemodynamic Responses During Tracheal Intubation
Interventions
Drug: Remifentanil
First Posted Date
2012-03-02
Last Posted Date
2016-04-20
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
80
Registration Number
NCT01542099
Locations
🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

Opioid Induced Swallowing Difficulties and Risk for Pulmonary Aspiration

First Posted Date
2011-12-20
Last Posted Date
2012-08-22
Lead Sponsor
Region Örebro County
Target Recruit Count
25
Registration Number
NCT01495377
Locations
🇸🇪

Örebro University Hospital, Örebro, Sweden

🇸🇪

University Hospital in Örebro, Örebro, Sweden

Comparison of Remifentanil With Dexmedetomidine or Midazolam in Regards of Sedation Effectivity and Postoperative Cognitive Functions in Cystoscopies

Not Applicable
Completed
Conditions
Postoperative Cognitive Functions
First Posted Date
2011-12-13
Last Posted Date
2011-12-13
Lead Sponsor
Gazi University
Target Recruit Count
40
Registration Number
NCT01491009
Locations
🇹🇷

Gazi University Faculty of Medicine Hospital, Ankara, Turkey

Efficacy of Two Bolus Doses of Remifentanil on the Incidence of Coughing During Emergence of Anesthesia

Not Applicable
Completed
Conditions
Cough
Anesthesia
Interventions
Drug: Remifentanil
First Posted Date
2011-12-09
Last Posted Date
2012-10-29
Lead Sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Target Recruit Count
180
Registration Number
NCT01489072
Locations
🇨🇦

Centre Hospitalier de l'Université de Montréal-Hôpital Notre-Dame, Montreal, Quebec, Canada

The EC90 of Remifentanil Blunting Hemodynamic Changes to Head Fixation

Not Applicable
Completed
Conditions
Brain Tumor
AVM
ICH
Interventions
Drug: remifentanil
First Posted Date
2011-12-09
Last Posted Date
2012-08-17
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
50
Registration Number
NCT01489137
Locations
🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

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