Remifentanil

Generic Name
Remifentanil
Brand Names
Ultiva
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5
CAS Number
132875-61-7
Unique Ingredient Identifier
P10582JYYK
Background

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

Indication

For use during the induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Immediate postoperative analgesia therapy, Induction and Maintenance of General Anesthesia, Monitored anesthesia care sedation
Clinical Trials
Related News

A Comparison of Remifentanil and Dexmedetomidine for Craniotomy Perioperative Hemodynamics and Postoperative Pain

First Posted Date
2011-01-04
Last Posted Date
2016-12-20
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
142
Registration Number
NCT01269918
Locations
🇺🇸

The Cleveland Clinic Foundation, Cleveland, Ohio, United States

🇺🇸

Cleveland Clinic Foundation, Cleveland, Ohio, United States

Effect of Remifentanil on Cough During Emergence From General Anesthesia : Trial to Compare Between Sevoflurane Anesthesia and Propofol Anesthesia

Phase 4
Completed
Conditions
Elective Thyroidectomy
Interventions
Drug: Remifentanil
First Posted Date
2010-11-15
Last Posted Date
2011-05-13
Lead Sponsor
Yonsei University
Target Recruit Count
70
Registration Number
NCT01240109
Locations
🇰🇷

Severance Hospital, Seoul, Korea, Republic of

Comparison Between Two Different Dosages of Remifentanil During Colonoscopy

Phase 4
Completed
Conditions
Colonoscopy
Interventions
Drug: Remifentanil
Drug: Meperidine
First Posted Date
2010-10-27
Last Posted Date
2012-02-01
Lead Sponsor
Ospedale San Raffaele
Target Recruit Count
90
Registration Number
NCT01229527
Locations
🇮🇹

San Raffaele Hospital, Milan, Italy

Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids

First Posted Date
2010-10-18
Last Posted Date
2018-06-15
Lead Sponsor
Stanford University
Target Recruit Count
10
Registration Number
NCT01222091
Locations
🇺🇸

Stanford University School of Medicine, Stanford, California, United States

Opioid Effects on Swallowing and Esophageal Sphincter Pressure

First Posted Date
2010-08-31
Last Posted Date
2012-02-02
Lead Sponsor
Region Örebro County
Target Recruit Count
14
Registration Number
NCT01191645
Locations
🇸🇪

Örebro University Hospital, Örebro, Sweden

The Effect of Nicardipine on Kidney Function During Orthognathic Surgery Under Hypotensive Anesthesia

Not Applicable
Completed
Conditions
Healthy Subjects
Interventions
Drug: Nicardipine
Drug: remifentanil
First Posted Date
2010-08-05
Last Posted Date
2013-06-13
Lead Sponsor
Yonsei University
Target Recruit Count
46
Registration Number
NCT01175746

Emergency Agitation in T&A

Not Applicable
Completed
Conditions
Healthy
Interventions
Drug: remifentanil
Drug: normal saline
First Posted Date
2010-06-29
Last Posted Date
2011-01-06
Lead Sponsor
Seoul National University Bundang Hospital
Target Recruit Count
42
Registration Number
NCT01152476
Locations
🇰🇷

Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of

A Low Dose Remifentanil Infusion During Tracheal Extubation in Surgical Intensive Care Unit Patients

Phase 4
Completed
Conditions
Tracheal Extubation
Interventions
Drug: Remifentanil
First Posted Date
2010-06-29
Last Posted Date
2020-03-27
Lead Sponsor
Severance Hospital
Target Recruit Count
50
Registration Number
NCT01152515
Locations
🇰🇷

Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea, Republic of

Effect of Intraoperative Remifentanil Infusion Rate on Postoperative Tolerance and Analgesic Consumption in Pediatric Laparoscopic Ureteroneocystostomy

Not Applicable
Conditions
Pediatrics
Interventions
Drug: remifentanil
First Posted Date
2010-06-22
Last Posted Date
2011-12-06
Lead Sponsor
Yonsei University
Target Recruit Count
60
Registration Number
NCT01147757
Locations
🇰🇷

Severance Hospital, Seoul, Korea, Republic of

Comparison of Sufentanil and Remifentanil Infusion During General Anaesthesia for Removal of Wisdom Teeth in Ambulatory Surgery

Phase 4
Completed
Conditions
Tooth Extractions
First Posted Date
2010-06-08
Last Posted Date
2014-07-08
Lead Sponsor
University Hospital, Clermont-Ferrand
Target Recruit Count
18
Registration Number
NCT01139671
Locations
🇫🇷

CHU Clermont-Ferrand, Clermont-Ferrand, France

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