Meperidine

Generic Name: Meperidine

Brand Names: Demerol

Drug Type: Small Molecule

Chemical Formula: C_₁₅H_₂₁NO_₂

CAS Number: 57-42-1

Unique Ingredient Identifier: 9E338QE28F

Background: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.

Indication: Used to control moderate to severe pain.

Associated Conditions: Severe Pain

Associated Therapies: Anesthesia therapy, Anesthetic premedication therapy, General Anesthesia, Local Anaesthesia therapy, Perioperative management therapy

Clinical Trials

Caudal Epidural Catheterization in Pediatric Renal Transplant: Effect on Hemodynamics and Pain After Surgery

Not Applicable

Completed

Conditions: Renal Failure

Interventions: Device: B-Braun, Perifix® ONE Paed, Germany
Drug: Pethidine
Drug: Fentanyl
Drug: Propofol
Drug: Bupivacaine

First Posted Date: 2014-01-16

Last Posted Date: 2014-10-06

Lead Sponsor: Cairo University

Target Recruit Count: 60

Registration Number: NCT02037802

Locations: 🇪🇬
Faculty of medicine, Cairo University, Cairo, Egypt

Etomidate vs. Midazolam for Sedation During ERCP

Phase 4

Completed

Conditions: Choledocholithiasis
Cholangiocarcinoma
Pancreatitis
Pancreatic Cancer

Interventions: Drug: Etomidate
Drug: Midazolam
Drug: Meperidine

First Posted Date: 2014-01-06

Last Posted Date: 2015-06-29

Lead Sponsor: Cheju Halla General Hospital

Target Recruit Count: 63

Registration Number: NCT02027311

Locations: 🇰🇷
1Digestive Disease Center and Department of Internal Medicine, Cheju Halla General Hospital, Jeju-si, Jeju Special Self-Governing Province, Korea, Republic of

Meperidine for Patients Expected to Have Poor Tolerance During Diagnostic Esophagogastroduodenoscopy.

Not Applicable

Completed

Conditions: Patients Undergoing Diagnostic EGD

Interventions: Drug: placebo
Drug: Meperidine

First Posted Date: 2013-09-24

Last Posted Date: 2017-03-20

Lead Sponsor: Dalin Tzu Chi General Hospital

Target Recruit Count: 110

Registration Number: NCT01948921

Locations: 🇨🇳
Buddhist Dalin Tzu Chi General Hospital, Chia-Yi, Taiwan

Cooling Plus Best Medical Treatment Versus Best Medical Treatment Alone for Acute Ischaemic Stroke

Phase 3

Terminated

Conditions: Acute Ischemic Stroke

Interventions: Device: Hypothermia
Drug: Buspirone
Drug: Pethidine

First Posted Date: 2013-04-16

Last Posted Date: 2019-10-02

Lead Sponsor: University of Erlangen-Nürnberg Medical School

Target Recruit Count: 98

Registration Number: NCT01833312

Locations: 🇩🇪
Department of Neurology, University Hospital Erlangen, Erlangen, Germany

A Comparison of Meperidine for Post-Cesarean Analgesia: Bolus Versus Infusion and Bolus

Not Applicable

Completed

Conditions: Cesarean Section

Interventions: Drug: Meperidine

First Posted Date: 2012-12-04

Last Posted Date: 2017-10-25

Lead Sponsor: Mercy Research

Target Recruit Count: 273

Registration Number: NCT01741259

Locations: 🇺🇸
Mercy Hospital St. Louis, Saint Louis, Missouri, United States

Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine.

Phase 4

Completed

Conditions: Disorders of Gallbladder, Biliary Tract and Pancrease

Interventions: Drug: Midazolam
Drug: Propofol
Drug: Meperidine

First Posted Date: 2012-10-18

Last Posted Date: 2013-10-22

Lead Sponsor: Prince of Songkla University

Target Recruit Count: 140

Registration Number: NCT01709422

Locations: 🇹🇭
NKC Institues of Gastroenterology and Hepatology, Prince of Songkla University, Hatyai, Songkhla, Thailand

Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy

Phase 4

Completed

Conditions: Diagnostic Colonoscopy Screening

Interventions: Drug: Remifentanil
Drug: Midazolam
Drug: placebo (for midazolam)
Drug: Meperidine
Drug: placebo (for meperidine)
Drug: placebo (for remifentanil)

First Posted Date: 2012-09-26

Last Posted Date: 2014-06-18

Lead Sponsor: Konkuk University Medical Center

Target Recruit Count: 60

Registration Number: NCT01693185

Locations: 🇰🇷
Konkuk University Medical Center, Seoul, Korea, Republic of

Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women

Phase 4

Completed

Conditions: Labor Pain

Interventions: Drug: Saline
Drug: Meperidine

First Posted Date: 2012-03-15

Last Posted Date: 2021-09-30

Lead Sponsor: Kanuni Sultan Suleyman Training and Research Hospital

Target Recruit Count: 250

Registration Number: NCT01555671

Locations: 🇹🇷
Prof.Dr.Cemil Tascioglu City Hospital, Istanbul, Turkey

Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy

Not Applicable

Completed

Conditions: Esophagogastroduodenoscopy

Interventions: Drug: Meperidine
Drug: normal saline

First Posted Date: 2012-03-08

Last Posted Date: 2012-03-08

Lead Sponsor: Dalin Tzu Chi General Hospital

Target Recruit Count: 140

Registration Number: NCT01547520

Locations: 🇨🇳
Dalin Tzu Chi General Hospital, Chia-Yi, Taiwan

Analgesic Effects of Intravenous Paracetamol on Labor Pain

Phase 4

Completed

Conditions: Labor Pain

Interventions: Drug: Acetaminophen
Drug: Meperidine

First Posted Date: 2011-07-14

Last Posted Date: 2011-07-14

Lead Sponsor: King Abdulaziz University

Registration Number: NCT01394731

Locations: 🇸🇦
King Abdulaziz Medical City, Riyadh, Central, Saudi Arabia

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