Hydroxyethyl Starch
- Generic Name
- Hydroxyethyl Starch
- Brand Names
- Hespan, Hextend, Volulyte, Voluven
- Drug Type
- Small Molecule
- CAS Number
- 9005-27-0
- Unique Ingredient Identifier
- 875Y4127EA
- Background
Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume.
HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
- Indication
An intravenous solution of hydroxyethyl starch is used to prevent shock following severe blood loss caused by trauma, surgery, or other issues.
- Associated Conditions
- Hypovolaemia
- Associated Therapies
- Granulocyte yield increase
Hydroxyethyl Starch (130/0.4) for Intravascular Volume Therapy in Liver Transplantation
- Conditions
- Intraoperative Complications
- Interventions
- Drug: 5% Albumin
- First Posted Date
- 2006-03-29
- Last Posted Date
- 2009-01-15
- Lead Sponsor
- Fresenius Kabi
- Target Recruit Count
- 53
- Registration Number
- NCT00308100
- Locations
- 🇨🇳
People's Hospital of Peking University, Beijing, China
Hetastarch and Bleeding Complications After Off-Pump Coronary Bypass Surgery
- Conditions
- Postoperative Hemorrhage
- First Posted Date
- 2006-03-27
- Last Posted Date
- 2006-05-22
- Lead Sponsor
- Kaiser Permanente
- Target Recruit Count
- 330
- Registration Number
- NCT00307138
- Locations
- 🇺🇸
Summit Medical Center, Oakland, California, United States
Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia
- Conditions
- Peripheral Vascular Disease
- Interventions
- First Posted Date
- 2006-03-08
- Last Posted Date
- 2008-05-16
- Lead Sponsor
- Biopure Corporation
- Target Recruit Count
- 16
- Registration Number
- NCT00300040
- Locations
- 🇿🇦
University of Stellenbosch, Tygerburg, South Africa
🇿🇦Milpark Hospital, Parktown West, Guateng, South Africa
🇬🇧John Radcliffe Hospital, Headington, Oxfordshire, United Kingdom
Influence of Hydroxyehtyl Starch (HES) on Hemorehology, Coagulation and Elimination Kinetics
- Conditions
- Stroke Patients Presenting Within 24 Hrs of Onset of Symptoms
- First Posted Date
- 2005-11-21
- Last Posted Date
- 2006-04-19
- Lead Sponsor
- Nizam's Institute of Medical Sciences University, India
- Target Recruit Count
- 20
- Registration Number
- NCT00255957
Drug Development Updates
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