Propofol

Generic Name
Propofol
Brand Names
Diprivan
Drug Type
Small Molecule
Chemical Formula
C12H18O
CAS Number
2078-54-8
Unique Ingredient Identifier
YI7VU623SF
Background

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.

Indication

Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions
-
Associated Therapies
Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy

Elucidation of the Mechanisms and Effects of Certain Anesthetic Interventions on Digestive Cancer Patients Subjected to Surgery

First Posted Date
2019-11-14
Last Posted Date
2021-02-10
Lead Sponsor
Iuliu Hatieganu University of Medicine and Pharmacy
Target Recruit Count
40
Registration Number
NCT04162535
Locations
🇷🇴

Institutu Regional de Gastroenterologie si Hepatologi Prof. Dr. O. Fodor, Cluj-Napoca, Cluj, Romania

Dexmedetomidine and Propofol in the Treatment of Emergence Agitation

Early Phase 1
Conditions
Interventions
First Posted Date
2019-10-29
Last Posted Date
2020-01-14
Lead Sponsor
RenJi Hospital
Target Recruit Count
120
Registration Number
NCT04142840
Locations
🇨🇳

Renji Hospital,Shanghai Jiao Tong University,School of Medicine, Shanghai, Shanghai, China

Comparison of the Effects of Dexmedetomidine and Propofol on the Cardiovascular Autonomic Nervous System During Spinal Anesthesia

First Posted Date
2019-10-29
Last Posted Date
2022-02-18
Lead Sponsor
Ajou University School of Medicine
Target Recruit Count
60
Registration Number
NCT04142502
Locations
🇰🇷

Ajou university school of medicine, Suwon, Gyeonggi-do, Korea, Republic of

Propofol vs Sevoflurane in Cyanotic Congenital Heart Disease

First Posted Date
2019-10-14
Last Posted Date
2022-04-07
Lead Sponsor
Cukurova University
Target Recruit Count
34
Registration Number
NCT04125550
Locations
🇹🇷

Cukurova University, Adana, Turkey

The Effects of Intravenous Anesthetics and Inhaled Anesthetics on Patients' Postoperative Sleep

First Posted Date
2019-10-10
Last Posted Date
2021-01-05
Lead Sponsor
Yanchao Yang
Target Recruit Count
74
Registration Number
NCT04123249
Locations
🇨🇳

Shengjing Hospital, Shenyang, Liaoning, China

A Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion in Subjects Undergoing Fiberoptic Bronchoscopy

Phase 3
Completed
Conditions
Interventions
First Posted Date
2019-10-01
Last Posted Date
2020-12-17
Lead Sponsor
Sichuan Haisco Pharmaceutical Group Co., Ltd
Target Recruit Count
267
Registration Number
NCT04111159
Locations
🇨🇳

West China Hospital,Sichuan University, Chengdu, China

Propofol and Magnesium Sulfate Intravenous Infusion During Endoscopic Sinus Surgery

First Posted Date
2019-09-06
Last Posted Date
2019-09-06
Lead Sponsor
Mansoura University
Target Recruit Count
50
Registration Number
NCT04078659
Locations
🇪🇬

Nabil A Abd El-Mageed, Mansoura, DK, Egypt

TIVA Admnistration and Autologous Fat Transfer in Breast Reconstruction

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2019-09-04
Last Posted Date
2020-09-10
Lead Sponsor
National and Kapodistrian University of Athens
Target Recruit Count
46
Registration Number
NCT04077827
Locations
🇬🇷

"Saint Savvas" Hospital, Athens, Greece

Volatile Anaesthesia and Perioperative Outcomes Related to Cancer Feasibility Study

First Posted Date
2019-08-30
Last Posted Date
2022-06-09
Lead Sponsor
Peter MacCallum Cancer Centre, Australia
Target Recruit Count
169
Registration Number
NCT04074460
Locations
🇦🇺

Peter MacCallum Cancer Centre, Melbourne, Australia

Propofol vs. Midazolam With Propofol for Sedative Endoscopy in Patients With Previous Paradoxical Reaction to Midazolam

Phase 2
Completed
Conditions
Interventions
First Posted Date
2019-08-28
Last Posted Date
2020-12-29
Lead Sponsor
DongGuk University
Target Recruit Count
30
Registration Number
NCT04072328
Locations
🇰🇷

Dongguk University Ilsan Hospital, Goyang-si, Gyeonggi-do, Korea, Republic of

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