Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Sedation With Sevoflurane Versus Propofol in Patients With Acute Respiratory Distress Syndrome Caused by COVID19 Infection
- Conditions
- Interventions
- First Posted Date
- 2020-04-24
- Last Posted Date
- 2021-07-27
- Target Recruit Count
- 19
- Registration Number
- NCT04359862
- Locations
- 🇪🇸
Hospital Universitario Cruces, Barakaldo, Bizkaia, Spain
🇪🇸Hospital Universitario Ramón y Cajal, Madrid, Spain
🇪🇸Hospital Clínico Universitario de Valencia, Valencia, Spain
Dose-response Curves Between Propofol and Intraoperative Electroencephalographic Patterns
- Conditions
- Interventions
- First Posted Date
- 2020-04-15
- Last Posted Date
- 2021-04-28
- Lead Sponsor
- University of Chile
- Target Recruit Count
- 15
- Registration Number
- NCT04345926
- Locations
- 🇨🇱
Hospital Clinico de la Universidad de Chile, Santiago, RM, Chile
🇨🇱Centro de Investigación Cínica Avanzada (CICA), Hospital Clinico de la Universidad de Chile, Santiago, RM, Chile
The Effect of Propofol on Dexamethasone-induced Perineal Pruritus
- First Posted Date
- 2020-04-07
- Last Posted Date
- 2022-02-25
- Lead Sponsor
- Yangzhou University
- Target Recruit Count
- 40
- Registration Number
- NCT04337073
- Locations
- 🇨🇳
Affiliated hospital of yangzhou university, Yangzhou, Jiangsu, China
Volatile Anaesthesia and Perioperative Outcomes Related to Cancer: The VAPOR-C Trial
- Conditions
- Interventions
- First Posted Date
- 2020-03-20
- Last Posted Date
- 2023-03-23
- Lead Sponsor
- Peter MacCallum Cancer Centre, Australia
- Target Recruit Count
- 3500
- Registration Number
- NCT04316013
- Locations
- 🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
🇦🇺Royal Brisbane and Women's Hospital, Herston, Queensland, Australia
🇦🇺RedCliffe Hospital, Redcliffe, Queensland, Australia
Namsos Anaesthesia Children Outcome Study
- First Posted Date
- 2020-03-03
- Last Posted Date
- 2024-03-01
- Lead Sponsor
- Helse Nord-Trøndelag HF
- Target Recruit Count
- 761
- Registration Number
- NCT04292457
- Locations
- 🇳🇴
ØNH Legen, Trondheim, Trøndelag, Norway
🇳🇴Namsos Hospital, Nord-Trondelag Hospital Trust, Namsos, Trøndelag, Norway
A Study to Evaluate the Differences in Pharmadynamics, Pharmacokinetics, and Safety Between Ciprofol and Propofol
- First Posted Date
- 2020-03-03
- Last Posted Date
- 2020-11-20
- Lead Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
- Target Recruit Count
- 18
- Registration Number
- NCT04294056
- Locations
- 🇨🇳
Sichuan Provincial People's Hospital, Chengdu, China
Mean Arterial Pressure Reduction Anesthesia Induction Using Propofol Bolus or Tritiated Target-infusion
- Conditions
- Interventions
- First Posted Date
- 2020-03-02
- Last Posted Date
- 2020-03-02
- Lead Sponsor
- Brasilia University Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT04291794
- Locations
- 🇧🇷
Hospital Universitário de Brasilia, Brasilia, Distrito Federal, Brazil
Prospective Study of Induction Medications Used in the Trauma RSI
- Conditions
- Interventions
- First Posted Date
- 2020-03-02
- Last Posted Date
- 2024-03-05
- Lead Sponsor
- University of Southern California
- Target Recruit Count
- 7000
- Registration Number
- NCT04291521
- Locations
- 🇺🇸
Keck School of Medicine of the University of Southern California, Los Angeles, California, United States
Anesthesia and Cancer Study: Colon Cancer
- Conditions
- Interventions
- First Posted Date
- 2020-02-06
- Last Posted Date
- 2023-11-22
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 797
- Registration Number
- NCT04259398
- Locations
- 🇰🇷
Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea, Republic of
🇰🇷Seoul National University Hospital, Seoul, Korea, Republic of
The Influence of Type of Anesthesia on Postoperative Pain
- Conditions
- Interventions
- First Posted Date
- 2020-01-27
- Last Posted Date
- 2023-12-22
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 468
- Registration Number
- NCT04239794
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
🇰🇷Seoul National University Bundang Hospital, Seoul, Korea, Republic of
🇰🇷Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea, Republic of
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.