Propofol

Generic Name
Propofol
Brand Names
Diprivan
Drug Type
Small Molecule
Chemical Formula
C12H18O
CAS Number
2078-54-8
Unique Ingredient Identifier
YI7VU623SF
Background

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.

Indication

Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions
-
Associated Therapies
Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy

Propofol Versus Sevoflurane Anesthesia in Pediatric Strabismus Surgery: Feasibility of BIS Monitoring

First Posted Date
2020-07-24
Last Posted Date
2021-06-10
Lead Sponsor
Sameh Fathy
Target Recruit Count
100
Registration Number
NCT04485117
Locations
🇪🇬

Department of Anesthesia, Mansoura University Hospitals, Mansoura, Dakahlia, Egypt

Anesthesia and Acute Kidney Injury After Nephrectomy

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2020-07-17
Last Posted Date
2024-12-02
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
324
Registration Number
NCT04474600
Locations
🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

Propofol vs Sevo for Paediatric Tumor Surgery

First Posted Date
2020-07-17
Last Posted Date
2022-03-16
Lead Sponsor
Hong Kong Children's Hospital
Target Recruit Count
100
Registration Number
NCT04475705
Locations
🇭🇰

Hong Kong Children's Hospital, Hong Kong, Hong Kong

Digital Sedation: Virtual Reality Hypnosis During Colonoscopy

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2020-07-10
Last Posted Date
2022-10-03
Lead Sponsor
Oncomfort
Target Recruit Count
90
Registration Number
NCT04465383
Locations
🇧🇪

Hôpital Erasme, Brussels, Belgium

Pupillary Response to Incremental Tetanic Stimulations Under Propofol-remifentanil TCI

First Posted Date
2020-07-10
Last Posted Date
2020-07-10
Lead Sponsor
Pr Isabelle CONSTANT
Target Recruit Count
18
Registration Number
NCT04465773
Locations
🇫🇷

Departement d'anesthesie Hopital Armand Trousseau, Paris, France

Safety Evaluation of Propofol Sedation for Magnetic Resonance Imaging in Pediatric Patients

First Posted Date
2020-07-02
Last Posted Date
2020-08-26
Lead Sponsor
Brugmann University Hospital
Target Recruit Count
99
Registration Number
NCT04455776
Locations
🇧🇪

Hôpital Universitaire des Enfants Reine Fabiola, Brussels, Belgium

f Adding Ketamine to Propofol For Drug-induced Sleep Endoscopy in Adult Patients With Obstructive Sleep Apnea

First Posted Date
2020-06-30
Last Posted Date
2021-12-28
Lead Sponsor
Zagazig University
Target Recruit Count
30
Registration Number
NCT04452383
Locations
🇪🇬

zagazig University, Zagazig, Sarkia, Egypt

Different Anesthesia Maintain Protocol Effect the Outcome of the Patients

First Posted Date
2020-06-23
Last Posted Date
2020-10-14
Lead Sponsor
China International Neuroscience Institution
Target Recruit Count
50
Registration Number
NCT04443946
Locations
🇨🇳

Xuanwu hospital, Beijing, Beijing, China

Comparison of Optic Nerve Sheath Diameter in Children Receiving Caudal Block According to Anesthetic Agents: Total Intravenous Anesthesia vs. Volatile Anesthesia

First Posted Date
2020-06-04
Last Posted Date
2022-05-05
Lead Sponsor
Yonsei University
Target Recruit Count
60
Registration Number
NCT04415905
Locations
🇰🇷

Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of

A Clinical Study of Remimazolam Tosilate in Patients Undergoing Bronchoscopy

Phase 3
Completed
Conditions
Interventions
First Posted Date
2020-05-22
Last Posted Date
2022-08-22
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
330
Registration Number
NCT04400201
Locations
🇨🇳

Peking Union Medical College Hospital, Beijing, China

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