Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Influence of Anesthesia on Mechanical Efficiency of Left Ventricle in Patients Undergoing Open Heart Surgery
- Conditions
- Interventions
- First Posted Date
- 2011-07-19
- Last Posted Date
- 2018-04-24
- Lead Sponsor
- Sheba Medical Center
- Target Recruit Count
- 28
- Registration Number
- NCT01397331
- Locations
- 🇮🇱
Department of Anesthesia and Intensive Care, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel
Effect of Propofol on Renal Injury in Patients Undergoing Valvular Heart Surgery
- First Posted Date
- 2011-06-29
- Last Posted Date
- 2013-04-12
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 112
- Registration Number
- NCT01384643
- Locations
- 🇰🇷
Severance Hospital, Seoul, Korea, Republic of
Reducing Delirium After Cardiac Surgery: A Multifaceted Approach Of Perioperative Care
- Conditions
- Interventions
- First Posted Date
- 2011-06-22
- Last Posted Date
- 2015-04-21
- Lead Sponsor
- University Health Network, Toronto
- Target Recruit Count
- 185
- Registration Number
- NCT01378741
- Locations
- 🇨🇦
University Health Network, Toronto, Ontario, Canada
The Energy Dose Study
- Conditions
- Interventions
- First Posted Date
- 2011-06-08
- Last Posted Date
- 2022-06-10
- Lead Sponsor
- Emory University
- Target Recruit Count
- 12
- Registration Number
- NCT01369147
- Locations
- 🇺🇸
Emory University Hospital, Atlanta, Georgia, United States
Trial Comparing Sedation for Endoscopy With Propofol Versus Midazolam in Cirrhotics
- First Posted Date
- 2011-05-19
- Last Posted Date
- 2011-05-19
- Lead Sponsor
- Govind Ballabh Pant Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT01356121
- Locations
- 🇮🇳
Prof Barjesh Chander Sharma, New Delhi, Delhi, India
Dexmedetomidine and Propofol in Children With History of Obstructive Sleep Apnea
- First Posted Date
- 2011-04-29
- Last Posted Date
- 2018-08-08
- Lead Sponsor
- Children's Hospital Medical Center, Cincinnati
- Target Recruit Count
- 60
- Registration Number
- NCT01344759
- Locations
- 🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
Postoperative Analgesia in Children After Propofol Anesthesia
- First Posted Date
- 2011-04-27
- Last Posted Date
- 2011-04-27
- Lead Sponsor
- University Clinical Centre of Kosova
- Target Recruit Count
- 100
- Registration Number
- NCT01342835
- Locations
- 🇷🇸
University Clinical Center of Kosovo, Pristina, Kosovo, Serbia
Providing "Good Sleep" for ICU Sedation
- Conditions
- Interventions
- First Posted Date
- 2011-04-27
- Last Posted Date
- 2018-12-19
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 3
- Registration Number
- NCT01342328
- Locations
- 🇺🇸
University of California San Francisco, San Francisco, California, United States
Oxidative Stress in Robot-assisted Laparoscopic Radical Prostatectomy
- First Posted Date
- 2011-04-13
- Last Posted Date
- 2011-04-13
- Lead Sponsor
- Chang Gung Memorial Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT01334424
- Locations
- 🇨🇳
Dept. of Anesthesiology, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan
Use of Lipid Emulsion or Nanoemulsion of Propofol on Children Undergoing Ambulatory Invasive Procedures.
- First Posted Date
- 2011-03-30
- Last Posted Date
- 2014-03-26
- Lead Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
- Registration Number
- NCT01326078
Drug Development Updates
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