Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures
- Conditions
- Interventions
- First Posted Date
- 2012-01-25
- Last Posted Date
- 2019-09-06
- Lead Sponsor
- Wake Forest University Health Sciences
- Target Recruit Count
- 33
- Registration Number
- NCT01516684
- Locations
- 🇺🇸
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States
Airway Dimension Study in Children Undergoing MRI Sedated With Propofol and Dexmedetomidine
- First Posted Date
- 2012-01-09
- Last Posted Date
- 2019-07-11
- Lead Sponsor
- Milton S. Hershey Medical Center
- Target Recruit Count
- 24
- Registration Number
- NCT01505933
- Locations
- 🇺🇸
Penn State Hershey Medical Center, Hershey, Pennsylvania, United States
Validation Study of Covariates Model (VaSCoM) for Propofol
- First Posted Date
- 2011-12-15
- Last Posted Date
- 2017-08-14
- Lead Sponsor
- Golden Jubilee National Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT01492712
- Locations
- 🇬🇧
Golden Jubilee National Hospital, Clydebank, United Kingdom
Compare Propofol to Fentanyl and Midazolam for Colonoscopy
- Conditions
- Interventions
- First Posted Date
- 2011-12-08
- Last Posted Date
- 2023-05-23
- Lead Sponsor
- Saint Joseph Mercy Health System
- Target Recruit Count
- 289
- Registration Number
- NCT01488045
- Locations
- 🇺🇸
Saint Joseph Mercy Hospital, Ann Arbor, Michigan, United States
Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy
- Conditions
- Interventions
- First Posted Date
- 2011-11-11
- Last Posted Date
- 2015-08-13
- Lead Sponsor
- Chang Gung Memorial Hospital
- Target Recruit Count
- 173
- Registration Number
- NCT01470170
- Locations
- 🇨🇳
Chang Gung Memorial Hospital, Taipei, Taiwan
Anesthesia and Lymphocytes Apoptosis
- Conditions
- Interventions
- First Posted Date
- 2011-10-28
- Last Posted Date
- 2015-05-22
- Lead Sponsor
- Ruijin Hospital
- Target Recruit Count
- 105
- Registration Number
- NCT01461551
- Locations
- 🇨🇳
Ruijin Hospital, Shanghai, Shanghai, China
Desflurane and Its Effect on Postoperative Morbidity and Mortality in Patients Undergoing Thoracic Surgery
- First Posted Date
- 2011-10-14
- Last Posted Date
- 2016-02-17
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 460
- Registration Number
- NCT01452256
- Locations
- 🇨🇭
University Hospital Zurich, Zurich, Switzerland
Sevoflurane, Propofol, Postoperative Pain
- Conditions
- First Posted Date
- 2011-09-21
- Last Posted Date
- 2013-04-10
- Lead Sponsor
- Tampere University Hospital
- Target Recruit Count
- 168
- Registration Number
- NCT01437462
- Locations
- 🇫🇮
Tampere University Hospital, Tampere, Finland
Desflurane Versus Propofol in the Sitting Position
- Conditions
- Interventions
- First Posted Date
- 2011-09-20
- Last Posted Date
- 2013-09-09
- Lead Sponsor
- Gachon University Gil Medical Center
- Target Recruit Count
- 40
- Registration Number
- NCT01436799
Propofol vs. Midazolam-based Balanced Propofol for Nonanesthesiologist Moderate Sedation in Colonoscopy
- First Posted Date
- 2011-09-05
- Last Posted Date
- 2016-05-25
- Lead Sponsor
- Infante, Javier Molina, M.D.
- Target Recruit Count
- 135
- Registration Number
- NCT01428882
- Locations
- 🇪🇸
Hospital San Pedro de Alcantara, Caceres, Spain
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.