Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium
- Conditions
- Interventions
- First Posted Date
- 2023-08-14
- Last Posted Date
- 2024-06-17
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 1332
- Registration Number
- NCT05990790
- Locations
- 🇦🇹
Medical University of Innsbruck, Innsbruck, Austria
🇦🇹Medical University of Vienna, Vienna, Austria
Performance Analysis of Hermetic Closed-loop Anesthesia Delivery System
- First Posted Date
- 2023-08-01
- Last Posted Date
- 2024-12-02
- Lead Sponsor
- Sir Ganga Ram Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT05967403
- Locations
- 🇮🇳
Nitin Sethi, New Delhi, Delhi, India
Esketamine and Propofol for Children With Autism Spectrum Disorder Undergoing Colonoscopy
- Conditions
- Interventions
- First Posted Date
- 2023-07-19
- Last Posted Date
- 2023-10-10
- Target Recruit Count
- 46
- Registration Number
- NCT05951465
- Locations
- 🇨🇳
Sir Run Run Hospital, Nanjing, Jiangsu, China
Cerebral Flow-metabolism Coupling During Adult Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-07-12
- Last Posted Date
- 2023-10-18
- Lead Sponsor
- Jason Chui
- Target Recruit Count
- 80
- Registration Number
- NCT05941494
- Locations
- 🇨🇦
London Health Sciences Centre, London, Ontario, Canada
Hemodynamic Responses of Dexmedetomidine, Lidocaine or Propofol Infusions During Laparoscopic Cholecystectomy
- Conditions
- Interventions
- First Posted Date
- 2023-07-10
- Last Posted Date
- 2023-07-11
- Lead Sponsor
- Menoufia University
- Target Recruit Count
- 80
- Registration Number
- NCT05937282
- Locations
- 🇪🇬
Menoufia University, Shibīn Al Kawm, Menoufia, Egypt
The Effects of Using Different Anesthetics on the Prognosis of Primary Tumors and Its Mechanism of Action
- Conditions
- Interventions
- First Posted Date
- 2023-07-03
- Last Posted Date
- 2023-09-28
- Target Recruit Count
- 1316
- Registration Number
- NCT05926336
- Locations
- 🇨🇳
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan
Effects of Propofol on Brain Function in Patients With Parkinson's Disease
- First Posted Date
- 2023-06-08
- Last Posted Date
- 2023-06-27
- Lead Sponsor
- Beijing Tiantan Hospital
- Target Recruit Count
- 600
- Registration Number
- NCT05895019
- Locations
- 🇨🇳
Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China
Efficacy and Safety of Ciprofol for General Anaesthesia in Patients Undergoing Transcatheter Aortic Valve Replacement
- Conditions
- Interventions
- First Posted Date
- 2023-05-31
- Last Posted Date
- 2024-10-14
- Target Recruit Count
- 124
- Registration Number
- NCT05881291
- Locations
- 🇨🇳
The Second Affiliated Hospital of Zhejiang University anesthesiology department, Hangzhou, Zhejiang, China
Propofol Versus Dexmedetomidine on the Incidence of Postoperative Nausea and Vomiting
- Conditions
- Interventions
- First Posted Date
- 2023-05-25
- Last Posted Date
- 2023-08-31
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 45
- Registration Number
- NCT05875077
- Locations
- 🇪🇬
Kasralaini Medical School, Cairo, Egypt
Efficacy and Safety of Fospropofol Disodium Versus Propofol for Deep Sedation in Critically Ill Patients
- Conditions
- Interventions
- First Posted Date
- 2023-05-23
- Last Posted Date
- 2023-07-05
- Lead Sponsor
- Xiaobo Yang, MD
- Target Recruit Count
- 60
- Registration Number
- NCT05870514
- Locations
- 🇨🇳
Wuhan Union Hospital, Wuhan, Hubei, China
Drug Development Updates
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