Morphine
- Generic Name
- Morphine
- Brand Names
- Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 57-27-2
- Unique Ingredient Identifier
- 76I7G6D29C
- Background
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorp...
- Indication
Morphine is used for the management of chronic, moderate to severe pain.
Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.
- Associated Conditions
- Chronic Pain, Severe Pain
- Associated Therapies
- -
Comparison of Paravertebral Block and Subcostal Transversus Abdominis Plane Block in Laparoscopic Nephrectomy
- Conditions
- Interventions
- First Posted Date
- 2023-02-10
- Last Posted Date
- 2024-03-12
- Lead Sponsor
- Istanbul University
- Target Recruit Count
- 91
- Registration Number
- NCT05723341
- Locations
- 🇹🇷
Istanbul University, Istanbul, Turkey
Evaluation of Effect of Intravenous Morphine vs Intravenous Ibuprofen and Acetaminophen vs Intravenous Ibuprofen
- Conditions
- Interventions
- First Posted Date
- 2022-11-29
- Last Posted Date
- 2023-09-07
- Lead Sponsor
- Isfahan University of Medical Sciences
- Target Recruit Count
- 150
- Registration Number
- NCT05630222
- Locations
- 🇮🇷
Al-Zahra University Hospital, Isfahan, Iran, Islamic Republic of
Ultrasound-guided Erector Spinae Plane Block Versus Paravertebral Block in Breast Cancer Patients Undergoing Mastectomy With Immediate Reconstruction - a Non-inferiority Trial
- Conditions
- Interventions
- First Posted Date
- 2022-10-21
- Last Posted Date
- 2022-10-21
- Lead Sponsor
- The Netherlands Cancer Institute
- Target Recruit Count
- 100
- Registration Number
- NCT05590559
- Locations
- 🇳🇱
NKI-AvL, Amsterdam, Noord-Holland, Netherlands
Intrathecal Morphine for Thoracoscopic Surgery
- First Posted Date
- 2022-10-20
- Last Posted Date
- 2022-10-20
- Lead Sponsor
- Cukurova University
- Target Recruit Count
- 46
- Registration Number
- NCT05588336
- Locations
- 🇹🇷
Cukurova University, Adana, Turkey
A Study to Assess the Effect of AZD4041 on Respiratory Drive in Recreational Opioid Users.
- First Posted Date
- 2022-10-20
- Last Posted Date
- 2024-11-15
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 45
- Registration Number
- NCT05587998
- Locations
- 🇺🇸
Research Site, Overland Park, Kansas, United States
Fentanyl Versus Morphine in Spinal Anesthesia for Caesarian Section - Study on Analgesia, Side Effects and Patient 's Satisfaction
- First Posted Date
- 2022-09-08
- Last Posted Date
- 2023-08-30
- Lead Sponsor
- Dr. Mihai Octavian Botea
- Target Recruit Count
- 160
- Registration Number
- NCT05533229
- Locations
- 🇷🇴
University of Oradea, Pelican Clinic Hospital, Oradea, Bihor, Romania
Intrathecal Morphine Versus Morphine-dexmedetomidine Combination for Postoperative Pain Control After Total Knee Replacement
- Conditions
- Interventions
- First Posted Date
- 2022-06-30
- Last Posted Date
- 2023-11-24
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 105
- Registration Number
- NCT05439564
- Locations
- 🇪🇬
Faculty of Medicine, Tantan University Hospital, Tanta, Egypt
Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery
- First Posted Date
- 2022-06-10
- Last Posted Date
- 2022-06-10
- Lead Sponsor
- University of Puerto Rico
- Target Recruit Count
- 100
- Registration Number
- NCT05413902
- Locations
- 🇵🇷
Puerto Rico Medical Center - University District Hospital, San Juan, Puerto Rico
A Study of SHR8554 Injection for the Treatment of Pain After Orthopedic Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-05-16
- Last Posted Date
- 2023-12-26
- Lead Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
- Target Recruit Count
- 320
- Registration Number
- NCT05375305
- Locations
- 🇨🇳
Shanghai Jiaotong University School of Medicine,Renji Hospital, Shanghai, Shanghai, China
Split Scripts for Pediatric Supracondylar Fracture Repairs
- First Posted Date
- 2022-05-12
- Last Posted Date
- 2023-11-21
- Lead Sponsor
- The Hospital for Sick Children
- Target Recruit Count
- 175
- Registration Number
- NCT05372133
- Locations
- 🇨🇦
The Hospital for Sick Children, Toronto, Ontario, Canada
Drug Development Updates
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