Octreotide

Generic Name
Octreotide
Brand Names
Bynfezia, Mycapssa, Sandostatin
Drug Type
Biotech
Chemical Formula
-
CAS Number
83150-76-9
Unique Ingredient Identifier
RWM8CCW8GP
Background

Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is a life-threat...

Indication

Octreotide by injection is used for the treatment of acromegaly and the reduction of flushing and diarrhea symptoms related to carcinoid tumors and/or vasoactive intestinal peptide (VIPoma) tumors. The delayed-release oral formulation is used for the long-term treatment of acromegaly in patients who tolerate and respond adequately to injectable octreotide an...

Associated Conditions
Acromegaly, Diarrhea, Metastatic Carcinoid Tumors
Associated Therapies
Long-term maintenance therapy

Recurrence Rates of Type I Gastric Neuroendocrine Tumors Treated With Long-acting Somatostatin Analogs

Conditions
First Posted Date
2019-01-23
Last Posted Date
2019-01-23
Lead Sponsor
Peking Union Medical College Hospital
Target Recruit Count
30
Registration Number
NCT03812939
Locations
🇨🇳

Peking Union Medical College Hospital, Beijing, Beijing, China

Comparison of 24-hours Versus 72-hours of Octreotide Infusion in Preventing Early Rebleed From Esophageal Varices

First Posted Date
2018-08-10
Last Posted Date
2024-01-08
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
160
Registration Number
NCT03624517
Locations
🇺🇸

The Ohio state University, Columbus, Ohio, United States

🇺🇸

University of Illinois at Chicago, Chicago, Illinois, United States

🇺🇸

University of Florida Health, Jacksonville, Florida, United States

and more 5 locations

A Four-Part Study to Assess the Safety, Tolerability, PK and PD of ONO-5788 in Healthy Adult Volunteers

First Posted Date
2018-06-27
Last Posted Date
2019-06-05
Lead Sponsor
Ono Pharmaceutical Co. Ltd
Target Recruit Count
76
Registration Number
NCT03571594
Locations
🇺🇸

Celerion, Tempe, Arizona, United States

Effect of Hyperglycemia on Microvascular Perfusion in Healthy Adults

First Posted Date
2018-05-09
Last Posted Date
2022-05-13
Lead Sponsor
University of Virginia
Target Recruit Count
15
Registration Number
NCT03520569
Locations
🇺🇸

University of Virginia, Charlottesville, Virginia, United States

A Study to Evaluate Patient Experience in the Therapy of Neuroendocrine Tumors Treated With Octreotide Long Acting Release Versus Lanreotide

First Posted Date
2017-09-21
Last Posted Date
2023-11-07
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
53
Registration Number
NCT03289741
Locations
🇺🇸

Memorial Sloan Kettering Commack, Commack, New York, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇺🇸

Memorial Sloan Kettering West Harrison, Harrison, New York, United States

and more 4 locations

Trial Using Octreotide to Enhance Liver Recovery After Hepatectomy

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2017-06-07
Last Posted Date
2024-02-14
Lead Sponsor
Fox Chase Cancer Center
Target Recruit Count
23
Registration Number
NCT03179995
Locations
🇺🇸

Temple University Hospital, Philadelphia, Pennsylvania, United States

🇺🇸

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

The Longitudinal Approach to Acromegaly: A Pattern of Treatment and Comparative Effectiveness Research

First Posted Date
2017-05-17
Last Posted Date
2022-03-16
Lead Sponsor
Ginkgo Leaf Center for Rare Disorders
Target Recruit Count
1965
Registration Number
NCT03158090
Locations
🇨🇳

China Acromegaly Organization, Guangzhou, Guangdong, China

RCT to Determine the Efficacy of Combining Hemospray With Medical Treatment in Acute Variceal Bleeding

First Posted Date
2017-02-23
Last Posted Date
2017-11-14
Lead Sponsor
Theodor Bilharz Research Institute
Target Recruit Count
105
Registration Number
NCT03061604
Locations
🇧🇪

Erasme Hospital , ULB, Brussels, Belgium

🇪🇬

Theodor Bilharz Research Institute, Giza, Egypt

Prevention of Postoperative Pancreatic Fistula by Somatostatin

Phase 3
Completed
Conditions
Interventions
First Posted Date
2016-12-22
Last Posted Date
2021-05-03
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
655
Registration Number
NCT03000946
Locations
🇫🇷

Cochin Hospital, Paris, France

🇫🇷

La Pitié Salpêtrière Hospital, Paris, France

Impact of Prophylactic Octreotide to Pancreatic Exocrine Secretion

Not Applicable
Conditions
Interventions
First Posted Date
2016-09-30
Last Posted Date
2016-09-30
Lead Sponsor
Saint Vincent's Hospital, Korea
Target Recruit Count
282
Registration Number
NCT02920567
Locations
🇰🇷

the Catholic University of Korea St. Vincent's Hospital, Suwon, Korea, Republic of

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