Ivermectin

Generic Name
Ivermectin
Brand Names
Sklice, Soolantra, Stromectol
Drug Type
Small Molecule
Chemical Formula
C95H146O28
CAS Number
70288-86-7
Unique Ingredient Identifier
8883YP2R6D
Background

Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A (22,23-dihydroavermectin B) and 10%...

Indication

Administered topically, ivermectin cream is indicated for the treatment of inflammatory lesions associated with rosacea. An over-the-counter ivermection lotion is commercially available and indicated for the topical treatment of head lice infestations in patients ≥6 months of age.
...

Associated Conditions
Ascariasis, Demodex Infestation, Enterobiasis, Filariasis caused by Loa Loa, Gnathostomiasis, Head Lice Infestation, Malaria, Myiasis, Onchocerciasis caused by Infection with Onchocerca volvulus, Rosacea, Scabies, Strongyloidiasis caused by Strongyloides Stercoralis Infection, Trichuriasis
Associated Therapies
-
Clinical Trials
Related News

Eval 3-Drug Therapy Diethylcarbamize, Albendazole and Ivermectin That Could Accelerate LF Elimination Outside of Africa

First Posted Date
2013-11-03
Last Posted Date
2018-10-09
Lead Sponsor
University Hospitals Cleveland Medical Center
Target Recruit Count
182
Registration Number
NCT01975441
Locations
🇵🇬

Papua New Guinean Institute for Medical Research, Maprik, East Sepik, Papua New Guinea

Safety Study of Combined Azithromycin, Ivermectin and Albendazole for Trachoma and Lymphatic Filariasis

First Posted Date
2013-07-19
Last Posted Date
2014-05-22
Lead Sponsor
Emory University
Registration Number
NCT01903057
Locations
🇲🇿

National Institute of Health, Ministry of Health, Maputo, Mozambique

Post-treatment Effects of Ivermectin (IVM) or Diethylcarbamazine (DEC) in Loiasis

Phase 4
Completed
Conditions
Loiasis
Interventions
Drug: Ivermectin
Drug: Diethylcarbamazine
First Posted Date
2012-05-08
Last Posted Date
2016-11-09
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
155
Registration Number
NCT01593722
Locations
🇨🇲

Filariasis and other Tropical Diseases Research Center, Yaounde, Cameroon

Multiple Versus Single Dose of Ivermectin for the Treatment of Strongyloidiasis

Phase 3
Completed
Conditions
Strongyloidiasis
Interventions
Drug: Ivermectin
First Posted Date
2012-04-04
Last Posted Date
2018-06-14
Lead Sponsor
Centro per le Malattie Tropicali
Target Recruit Count
312
Registration Number
NCT01570504
Locations
🇮🇹

Unità di Malattie Infettive, Anna Meyer Children's Universisty Hospital, Florence, Italy

🇪🇸

Unitat Medicina Tropical i Salut Internacional Drassanes, Barcelona, Spain

🇪🇸

FCRB, Hospital Clinic de Barcelona, Barcelona, Spain

and more 6 locations

Safety and Efficacy of Drug Combinations Against Trichuris Trichiura

First Posted Date
2010-01-15
Last Posted Date
2010-01-15
Lead Sponsor
DBL -Institute for Health Research and Development
Target Recruit Count
750
Registration Number
NCT01050452
Locations
🇺🇬

Vector Control Division, Kampala, Uganda

Ivermectin Solution Bioequivalence Study - With Food

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: ivermectin
First Posted Date
2009-06-16
Last Posted Date
2011-10-06
Lead Sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Target Recruit Count
24
Registration Number
NCT00921674

Ivermectin Solution Bioequivalence Study - With Food (Repeat)

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: ivermectin
First Posted Date
2009-06-16
Last Posted Date
2011-10-06
Lead Sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Target Recruit Count
34
Registration Number
NCT00921219

Ivermectin Solution Bioequivalence Study - Fasted

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: ivermectin
First Posted Date
2009-06-16
Last Posted Date
2011-10-06
Lead Sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Target Recruit Count
24
Registration Number
NCT00921154
Locations
🇮🇪

Shandon Clinic, Cork, Co. Cork, Ireland

Ivermectin in the Treatment of Head Lice

Phase 3
Completed
Conditions
Lice Infestations
Interventions
Drug: ivermectin
Drug: malathion
First Posted Date
2009-01-09
Last Posted Date
2011-08-22
Lead Sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Target Recruit Count
812
Registration Number
NCT00819520
Locations
🇮🇱

Chaim Sheba Medical Centre, Tel Hashomer, Israel

🇬🇧

Synexus Clinical Research Centre, Reading, Berks, United Kingdom

🇫🇷

Hopital Avicenne, Bobigny, Paris, France

and more 1 locations

Study Comparing Moxidectin And Ivermectin In Subjects With Onchocerca Volvulus Infection

Phase 3
Completed
Conditions
Onchocerciasis
Interventions
Drug: Moxidectin
Drug: Ivermectin
First Posted Date
2008-11-14
Last Posted Date
2018-01-31
Lead Sponsor
Medicines Development for Global Health
Target Recruit Count
1497
Registration Number
NCT00790998
Locations
🇨🇩

Centre de Recherche en Maladies Tropicales de l'Ituri, Rethy, Congo, The Democratic Republic of the

🇱🇷

Liberian Institute for Biomedical Research Clinical Research Center, Bolahun, Lofa County, Liberia

🇨🇩

Centre de Recherche Clinique de Butembo - Université Catholique du Graben, Butembo, Congo, The Democratic Republic of the

and more 1 locations
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