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Etomidate

Generic Name
Etomidate
Brand Names
Amidate
Drug Type
Small Molecule
Chemical Formula
C14H16N2O2
CAS Number
33125-97-2
Unique Ingredient Identifier
Z22628B598
Background

Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.

Indication

Used in the induction of general anesthesia.

Associated Therapies
General Anesthesia
Clinical Trials
Related News

Rocuronium Consumption in Etomidate-based and Propofol-based General Anesthesia Under Sevoflurane

Not Applicable
Completed
Conditions
Neuromuscular Monitoring
Interventions
Drug: MAC 0.75
Drug: MAC 1.0
Drug: MAC 0.5
First Posted Date
2016-03-17
Last Posted Date
2016-03-17
Lead Sponsor
Tianjin Medical University General Hospital
Target Recruit Count
175
Registration Number
NCT02711917

Neurorestorative Effects of Electroconvulsive Therapy (ECT) in Patients With Severe Late Life Depression

Not Applicable
Completed
Conditions
Depression
Interventions
Procedure: ECT
First Posted Date
2016-01-28
Last Posted Date
2016-01-28
Lead Sponsor
Universitaire Ziekenhuizen KU Leuven
Target Recruit Count
110
Registration Number
NCT02667353

Target Controlled Infusion of Etomidate or Propofol for Anesthesia of Thoracoscopic Mitral Valve Replacement Surgery

Phase 4
Conditions
Hemodynamic Instability
Delirium
Interventions
Device: Bispectral Index Monitor
Drug: Induction of anesthesia
Drug: Maintenance of anesthesia
Other: Tracheal Intubation
First Posted Date
2016-01-01
Last Posted Date
2016-01-01
Lead Sponsor
Xijing Hospital
Target Recruit Count
110
Registration Number
NCT02644980

Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial

Phase 4
Completed
Conditions
Respiratory Arrest
Cardiopulmonary Arrest
Interventions
Procedure: Emergency Endotracheal Intubation
Device: Mechanical Ventilation
First Posted Date
2015-12-31
Last Posted Date
2021-12-15
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
801
Registration Number
NCT02643381
Locations
🇺🇸

Parkland Hospital, Dallas, Texas, United States

Effects and Mechanism of Pretreatment With Dexmedetomidine to Etomidate Induce Myoclonus

Phase 4
Conditions
Myoclonus
Interventions
Drug: normal saline
Drug: midazolam，fentanyl，rocuronium
First Posted Date
2015-08-10
Last Posted Date
2015-08-10
Lead Sponsor
Tang-Du Hospital
Target Recruit Count
132
Registration Number
NCT02518789

Comparison the Effects of Etomidate and Sevoflurane During Electroconvulsive Therapy

Phase 4
Completed
Conditions
Anesthesia
ECT
Interventions
First Posted Date
2015-07-16
Last Posted Date
2019-01-23
Lead Sponsor
Inonu University
Target Recruit Count
25
Registration Number
NCT02500225

Helping Stroke Patients With ThermoSuit Cooling

Not Applicable
Terminated
Conditions
Brain Ischemia
Stroke
Interventions
Device: ThermoSuit Cooling Induction
Procedure: Neurothrombectomy
First Posted Date
2015-05-25
Last Posted Date
2023-06-06
Lead Sponsor
Life Recovery Systems
Target Recruit Count
14
Registration Number
NCT02453373
Locations
🇺🇸

Geisinger Medical Center, Danville, Pennsylvania, United States

🇺🇸

U of SC School of Medicine, Columbia, South Carolina, United States

🇺🇸

Tulane University, New Orleans, Louisiana, United States

and more 1 locations

The Feasibility of Different Doses of Etomidate Admixed With Propofol in Induced Abortion: A Randomized, Double Blind Controlled Trial

Phase 4
Conditions
Induced Abortion
Anesthesia
Interventions
First Posted Date
2014-08-05
Last Posted Date
2014-08-05
Lead Sponsor
Third Affiliated Hospital of Zhengzhou University
Target Recruit Count
150
Registration Number
NCT02208596

Effect of Induction and Maintenance of Anesthesia With Etomidate on Hemodynamics and Oxidative Stress in Diabetic Patients

First Posted Date
2014-07-28
Last Posted Date
2014-07-28
Lead Sponsor
Zhujiang Hospital
Target Recruit Count
60
Registration Number
NCT02202239

Comparison of Etomidate, Propofol and Etomidate-propofol Combination in Terms of Effects on Haemodynamic Response to Intubation

Phase 4
Completed
Conditions
Induction of Anaesthesia
Interventions
Drug: etomidate-propofol
First Posted Date
2014-07-10
Last Posted Date
2014-08-13
Lead Sponsor
T.C. ORDU ÜNİVERSİTESİ
Target Recruit Count
90
Registration Number
NCT02186990
Locations
🇹🇷

Anesthesiology and Reanimation Dept. Ordu University Training and Research Hospital, Altınordu, Ordu, Turkey

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