Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Comparison of Intra-articular Dexmedetomidine and Magnesium in Postoperative Pain
- Conditions
- Interventions
- First Posted Date
- 2018-03-27
- Last Posted Date
- 2018-11-13
- Lead Sponsor
- Derince Training and Research Hospital
- Target Recruit Count
- 62
- Registration Number
- NCT03479216
- Locations
- 🇹🇷
Derince Training and Research Hospital, Kocaeli, Derince, Turkey
Alcohol: Thiamine and or Magnesium 1
- Conditions
- Interventions
- First Posted Date
- 2018-03-15
- Last Posted Date
- 2019-07-31
- Lead Sponsor
- Glasgow Royal Infirmary
- Target Recruit Count
- 127
- Registration Number
- NCT03466528
- Locations
- 🇬🇧
Glasgow Royal Infirmary, Glasgow, United Kingdom
Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal
- Conditions
- Interventions
- First Posted Date
- 2018-03-12
- Last Posted Date
- 2019-08-21
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 40
- Registration Number
- NCT03461328
- Locations
- 🇪🇬
Anesthesia department - Faculty of medicine- Cairo University, Cairo, Egypt
Caudal Dexmetedomedine Versus Magnesium in Orthopedic Pediatric Surgeries
- Conditions
- Interventions
- First Posted Date
- 2018-03-09
- Last Posted Date
- 2018-03-09
- Lead Sponsor
- Hagar hassanein refaee
- Target Recruit Count
- 36
- Registration Number
- NCT03460041
- Locations
- 🇪🇬
Cairo University faculty, Cairo, Egypt
Analgesic Efficacy of Two Adjuvants During Spinal Anaesthesia.
- Conditions
- Interventions
- First Posted Date
- 2018-03-08
- Last Posted Date
- 2018-03-08
- Lead Sponsor
- Centre de Maternité de Monastir
- Target Recruit Count
- 150
- Registration Number
- NCT03458078
- Locations
- 🇹🇳
Chu Tahar Sfar, Mahdia, Tunisia
🇹🇳Centre de Maternité de Monastir, Monastir, Tunisia
Magnesium for Shivering in Epidural Lidocaine Deliveries
- First Posted Date
- 2018-02-20
- Last Posted Date
- 2021-02-26
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 90
- Registration Number
- NCT03439358
- Locations
- 🇨🇦
BC Women's Hospital, Vancouver, British Columbia, Canada
Risk Analysis of Intensive Care Mangement on Maternal and Fetal Outcome of Severe Preeclampsia and Eclampsia
- First Posted Date
- 2018-01-26
- Last Posted Date
- 2018-01-26
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 1238
- Registration Number
- NCT03412552
- Locations
- 🇪🇬
Kasr Alainy medical school, Cairo, Egypt
Epidural Magnesium Sulfate for Post-thoracotomy Pain Control
- First Posted Date
- 2017-11-17
- Last Posted Date
- 2018-04-04
- Target Recruit Count
- 80
- Registration Number
- NCT03343548
- Locations
- 🇮🇷
Shadi Baniasadi, Tehran, Iran, Islamic Republic of
Magnesium Sulphate for Attenuation of Hemodynamic Pressor Response After Myfield's Clamp Application
- First Posted Date
- 2017-10-24
- Last Posted Date
- 2017-10-24
- Lead Sponsor
- El-Sahel Teaching Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT03318471
Discontinuation of Magnesium Sulfate After Delivery in Women With Severe Preeclampsia. A Randomized Controlled Trial
- First Posted Date
- 2017-10-23
- Last Posted Date
- 2017-10-23
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 100
- Registration Number
- NCT03318211
Drug Development Updates
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