Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Tocolysis in Prevention of Preterm Labor
- Conditions
- Interventions
- First Posted Date
- 2017-10-02
- Last Posted Date
- 2017-10-02
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 300
- Registration Number
- NCT03298191
- Locations
- 🇪🇬
Mohamed Atef Mohamed, Sohag, Egypt
Non-invasive Ventilation vs. Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma
- First Posted Date
- 2017-09-28
- Last Posted Date
- 2018-05-02
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 100
- Registration Number
- NCT03296579
Antiarrhythmic and Cardioprotective Effects of Atorvastatin Versus Magnesium Sulfate in Cardiac Valve Replacement Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-09-21
- Last Posted Date
- 2018-02-13
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 96
- Registration Number
- NCT03289429
- Locations
- 🇪🇬
Assiut University, Assiut, Egypt
Magnesium and Postoperative Pain
- Conditions
- Interventions
- First Posted Date
- 2017-08-17
- Last Posted Date
- 2018-04-18
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 24
- Registration Number
- NCT03253224
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of
Effect of Administering Intravenous Magnesium Sulfate on Fetal Cardiotocography and Neonatal Outcome in Preeclamptic Patients
- First Posted Date
- 2017-08-02
- Last Posted Date
- 2017-08-02
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 100
- Registration Number
- NCT03237000
- Locations
- 🇪🇬
Kasr Alainy medical school, Cairo, Egypt
The Effect of Intraoperative Magnesium Sulfate Infusion on the Occurrence of Emergence Agitation
- Conditions
- Interventions
- First Posted Date
- 2017-07-05
- Last Posted Date
- 2023-09-11
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 92
- Registration Number
- NCT03208452
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of
The Effect of Intraoperative Magnesium Sulfate Infusion on the Postoperative Recovery
- Conditions
- Interventions
- First Posted Date
- 2017-07-02
- Last Posted Date
- 2018-04-20
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 11
- Registration Number
- NCT03206008
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, department of Anesthesia and pain, Seongnam, Gyenggo-do, Korea, Republic of
Treatment of Renal Colic in the Emergency Departement (ED).
- Conditions
- Interventions
- First Posted Date
- 2017-06-27
- Last Posted Date
- 2022-08-10
- Lead Sponsor
- University of Monastir
- Target Recruit Count
- 600
- Registration Number
- NCT03199924
- Locations
- 🇹🇳
Emergency department of university hospital Fattouma Bourguiba of Monastir Monastir, Monastir Tunisia, Monastir, Tunisia
Efficacy and Safety of 1 g Vs 2 g Per Hour Intravenous Maintenance Dose of MgSO4 in Women With Severe Pre-eclampsia
- First Posted Date
- 2017-05-23
- Last Posted Date
- 2020-04-24
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 222
- Registration Number
- NCT03164304
- Locations
- 🇪🇬
Assiut University, woman health hospital, Assiut, Egypt
Dexmedetomidine Versus Magnesium Sulphate for Caesarean Delivery
- Conditions
- Interventions
- First Posted Date
- 2017-03-01
- Last Posted Date
- 2017-03-01
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 78
- Registration Number
- NCT03067896
- Locations
- 🇪🇬
Ahmed Talaat Ahmed, Assiut, Egypt
Drug Development Updates
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