MedPath

Magnesium sulfate

Generic Name
Magnesium sulfate
Brand Names
Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
Drug Type
Small Molecule
Chemical Formula
MgO4S
CAS Number
7487-88-9
Unique Ingredient Identifier
ML30MJ2U7I
Background

A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)

Indication

Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.

Associated Conditions
Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
Associated Therapies
Bowel preparation therapy, Soaking aid for minor sprains and bruises
Clinical Trials
Related News

Comparison Between a 1L of Polyethylene Glycol+Ascorbic Acid as a Split Dose Bowel Preparation for Colonoscopy

Phase 4
Conditions
Colonic Polyp
Colon Adenoma
Interventions
Drug: CleanViewAL
First Posted Date
2021-02-17
Last Posted Date
2021-07-07
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
200
Registration Number
NCT04758156
Locations
🇰🇷

Seoul national university hospital, Seoul, Korea, Republic of

Magnesium Sulphate Injection in Treatment of Myofascial Trigger Points

Phase 4
Completed
Conditions
Trigger Point Pain, Myofascial
Interventions
Drug: Saline
First Posted Date
2021-02-05
Last Posted Date
2021-12-07
Lead Sponsor
Fayoum University
Target Recruit Count
180
Registration Number
NCT04742140
Locations
🇪🇬

Faculty of Dentistry, Fayoum, Egypt

Efficacy of Magnesium Sulfate Bolus in Pediatric Patients With Bronchiolitis

Phase 2
Active, not recruiting
Conditions
Bronchiolitis, Viral
Interventions
First Posted Date
2021-02-05
Last Posted Date
2024-10-10
Lead Sponsor
University of Louisville
Target Recruit Count
40
Registration Number
NCT04740294
Locations
🇺🇸

Norton Children's Hospital, Louisville, Kentucky, United States

Beneficial Effect of Intravenous Magnesium Sulphate in Term Neonates With Hypoxic Ischemic Encephalopathy(HIE)

Phase 2
Completed
Conditions
HIE
Interventions
First Posted Date
2021-01-12
Last Posted Date
2021-01-12
Lead Sponsor
Services Institute of Medical Sciences, Pakistan
Target Recruit Count
200
Registration Number
NCT04705142
Locations
🇵🇰

Services Institute of Medical Sciences, Lahore, Lahore, Punjab, Pakistan

Shivering Control After Percutaneous Nephrolithotomy

Phase 3
Completed
Conditions
Shivering Control
Interventions
Drug: Aminoacid
First Posted Date
2021-01-05
Last Posted Date
2021-06-01
Lead Sponsor
Assiut University
Target Recruit Count
80
Registration Number
NCT04695613
Locations
🇪🇬

Assiut university, Assiut, Egypt

Effects Magnesium Sulfate and Labetalol Infusion on Peripheral Perfusion and Pain in Nasal Surgeries

Phase 1
Completed
Conditions
Postoperative Pain
Peripheral Perfusion
Interventions
First Posted Date
2020-12-29
Last Posted Date
2022-02-24
Lead Sponsor
Zagazig University
Target Recruit Count
50
Registration Number
NCT04688203
Locations
🇪🇬

Alshaimaa Abdel Fattah Kamel, Zagazig, Egypt

Mgso4 as Neuroprotective in Post Traumatic Brain Injury

Phase 3
Completed
Conditions
Magnesium Sulphate
Traumatic Brain Injury
Brain
Injury
Interventions
Drug: Placebo
First Posted Date
2020-11-30
Last Posted Date
2020-11-30
Lead Sponsor
Osama Mohamed Abdelwahab
Target Recruit Count
60
Registration Number
NCT04646876
Locations
🇪🇬

Faculty of medicine , Cairo university, Cairo, Egypt

Magnesium for Peroral Endoscopic Myotomy

Phase 2
Completed
Conditions
Esophageal Spasm
Interventions
Drug: Normal Saline
First Posted Date
2020-11-20
Last Posted Date
2024-05-21
Lead Sponsor
Stanford University
Target Recruit Count
92
Registration Number
NCT04638881
Locations
🇺🇸

Stanford Health Care, Stanford, California, United States

Evaluation of the Role of Low Dose Magnesium Sulfate in Anesthesia for Toxic Goiter Resection

Phase 4
Completed
Conditions
Haemodynamic Stability
Interventions
First Posted Date
2020-11-17
Last Posted Date
2022-09-07
Lead Sponsor
Fayoum University Hospital
Target Recruit Count
60
Registration Number
NCT04632524
Locations
🇪🇬

Atef, Fayoum, Egypt

Smooth Extubation With Magnesium Sulphate for General Anesthesia With Endotracheal Intubation

Phase 4
Completed
Conditions
Smooth Extubation
Interventions
Drug: Normal saline
First Posted Date
2020-11-05
Last Posted Date
2021-08-19
Lead Sponsor
Fayoum University Hospital
Target Recruit Count
60
Registration Number
NCT04617652
Locations
🇪🇬

Fayoum University hospital, Fayoum, Fayoum, Madīnat Al Fayyūm, Faiyum Governorate, Egypt, Egypt

© Copyright 2025. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy