Tizanidine
- Generic Name
- Tizanidine
- Brand Names
- Zanaflex
- Drug Type
- Small Molecule
- Chemical Formula
- C9H8ClN5S
- CAS Number
- 51322-75-9
- Unique Ingredient Identifier
- 6AI06C00GW
- Background
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition.
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- Indication
Tizanidine is indicated for the relief of muscle spasticity, which can interfere with daily activities. The general recommendation is to reserve tizanidine use for periods of time when there is a particular need for relief, as it has a short duration of action .
- Associated Conditions
- Acute Low Back Pain, Drug Withdrawal Headache, Insomnia, Migraine, Pain, Seizures, Spasticity, Muscle
- Associated Therapies
- Withdrawal From Addictive Substance; Detoxification
Single Dose Monoaminergic Drive in Stroke
- First Posted Date
- 2024-10-30
- Last Posted Date
- 2024-10-30
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 64
- Registration Number
- NCT06666673
- Locations
- 🇺🇸
Northwestern University, Dept. of PTHMS 645 N Michigan Ave, Suite 1100, Chicago, Illinois, United States
Assess the Effect of Metaxalone 640 mg (M640) Compared to Tizanidine 8 mg on Truck Driving Ability and Cognition
- First Posted Date
- 2024-04-24
- Last Posted Date
- 2024-06-07
- Lead Sponsor
- Primus Pharmaceuticals
- Target Recruit Count
- 20
- Registration Number
- NCT06382662
- Locations
- 🇺🇸
Sun Valley Arthritis Center, Peoria, Arizona, United States
Effect of Tizanidine on Postoperative Urinary Retention After Sacrospinous Suspension
- Conditions
- Interventions
- First Posted Date
- 2024-02-14
- Last Posted Date
- 2024-11-19
- Lead Sponsor
- NorthShore University HealthSystem
- Target Recruit Count
- 30
- Registration Number
- NCT06258785
- Locations
- 🇺🇸
NorthShore University Health System, Skokie, Illinois, United States
CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial
- Conditions
- Interventions
- First Posted Date
- 2023-09-07
- Last Posted Date
- 2024-08-16
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 375
- Registration Number
- NCT06027099
Opioid-Free Pain Protocol After Shoulder Arthroplasty
- First Posted Date
- 2022-08-05
- Last Posted Date
- 2024-01-12
- Lead Sponsor
- Henry Ford Health System
- Target Recruit Count
- 80
- Registration Number
- NCT05488847
- Locations
- 🇺🇸
Henry Ford Health, Detroit, Michigan, United States
Gabapentin and Tizanidine for Insomnia in Chronic Pain
- Conditions
- Interventions
- First Posted Date
- 2020-06-12
- Last Posted Date
- 2023-12-08
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 24
- Registration Number
- NCT04429347
- Locations
- 🇺🇸
Center for Pain Medicine, UC San Diego, La Jolla, California, United States
Ibuprofen Plus Metaxolone, Tizanidine, or Baclofen for Low Back Pain
- Conditions
- Interventions
- First Posted Date
- 2017-03-03
- Last Posted Date
- 2020-08-12
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 320
- Registration Number
- NCT03068897
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Tizanidine and Superficial Cervical Block on Pain After Thyroidectomy
- Conditions
- Interventions
- First Posted Date
- 2016-04-01
- Last Posted Date
- 2016-12-20
- Lead Sponsor
- Ataturk University
- Target Recruit Count
- 60
- Registration Number
- NCT02725359
- Locations
- 🇹🇷
Ataturk University, Yakutiye, Erzurum, Turkey
Tizanidine and Pain After Herniorrhaphy
- First Posted Date
- 2013-12-20
- Last Posted Date
- 2015-04-23
- Lead Sponsor
- Diskapi Teaching and Research Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT02016443
- Locations
- 🇹🇷
Diskapi Yildirim Beyazit training and research hospital, Ankara, Turkey
A Study on the Effect of Vemurafenib on the Pharmacokinetics of a Single Dose of Tizanidine in Patients With BRAFV600 Mutation-Positive Metastatic Malignancies
- Conditions
- Interventions
- First Posted Date
- 2013-05-01
- Last Posted Date
- 2017-03-20
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 18
- Registration Number
- NCT01844674
- Locations
- 🇨🇾
Bank of Cyprus Oncology Center, Nicosia, Cyprus
🇨🇦CSSS champlain - Charles-Le Moyne, Greenfield Park, Quebec, Canada
🇺🇸Karmanos Cancer Center, Detroit, Michigan, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.