Tramadol
- Generic Name
- Tramadol
- Brand Names
- Conzip, Durela, Qdolo, Ralivia, Ryzolt, Seglentis, Tridural, Ultracet, Ultram, Zytram
- Drug Type
- Small Molecule
- Chemical Formula
- C16H25NO2
- CAS Number
- 27203-92-5
- Unique Ingredient Identifier
- 39J1LGJ30J
- Background
Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is consider...
- Indication
Tramadol is approved for the management of moderate to severe pain in adults.
Tramadol is also used off-label in the treatment of premature ejaculation.
- Associated Conditions
- Acute Pain, Premature Ejaculation, Severe Pain, Acute, moderate, severe Pain, Moderate Pain
- Associated Therapies
- -
RCT on Ketorolac and Tramadol in Bone Fractures Pain of Child
- First Posted Date
- 2007-11-19
- Last Posted Date
- 2017-08-24
- Lead Sponsor
- IRCCS Burlo Garofolo
- Target Recruit Count
- 133
- Registration Number
- NCT00560443
- Locations
- 🇮🇹
IRCCS Burlo Garofolo, Trieste, Italy
Comparison of Butorphanol and Tramadol Associated Patient-Controlled Analgesia (PCA) After Hysterectomy
- Conditions
- Interventions
- First Posted Date
- 2007-08-02
- Last Posted Date
- 2009-03-31
- Lead Sponsor
- Nanjing Medical University
- Target Recruit Count
- 841
- Registration Number
- NCT00510666
- Locations
- 🇨🇳
Nanjing Maternal and Child Care Hospital, Nanjing, Jiangsu, China
The Discriminative Effects of Tramadol in Humans
- Conditions
- Interventions
- First Posted Date
- 2007-07-11
- Last Posted Date
- 2017-10-17
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 20
- Registration Number
- NCT00499746
- Locations
- 🇺🇸
Behavioral Pharmacology Research Unit, Baltimore, Maryland, United States
Tramadol and Pain Sensitization
- Conditions
- First Posted Date
- 2007-06-15
- Last Posted Date
- 2009-03-17
- Lead Sponsor
- University Hospital, Clermont-Ferrand
- Target Recruit Count
- 12
- Registration Number
- NCT00487175
- Locations
- 🇫🇷
CIC, Clermont-Ferrand, France
Norspan® Patches Versus Tramadol in Subjects With Chronic, Moderate to Severe Osteoarthritis Pain in the Hip Knee and/or Lumbar Spine
- First Posted Date
- 2007-01-25
- Last Posted Date
- 2010-02-01
- Lead Sponsor
- Norpharma A/S
- Target Recruit Count
- 120
- Registration Number
- NCT00426647
- Locations
- 🇫🇮
Dr. Olavi Airaksinen, Oma Lääkäri Oy, Vuorikatu 20, Kuopio, Finland
Comparison of Tramadol vs Remifentanyl Patient Controlled Analgesia for Second Trimester Abortions
- Conditions
- First Posted Date
- 2006-08-08
- Last Posted Date
- 2015-11-24
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 40
- Registration Number
- NCT00361686
- Locations
- 🇮🇱
Rabin Medical Center, Petach Tiqvah, Israel
Comparison Between Tramadol Hcl and Other Analgesics in the Treatment of Renal Colic
- Conditions
- First Posted Date
- 2006-04-05
- Last Posted Date
- 2009-02-17
- Lead Sponsor
- Hadassah Medical Organization
- Target Recruit Count
- 100
- Registration Number
- NCT00310908
- Locations
- 🇮🇱
Hadassah Medical Organization, Jerusalem, Israel
Assessment of Tramadol as a Treatment for Opioid Addiction
- First Posted Date
- 2006-03-10
- Last Posted Date
- 2015-04-17
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 9
- Registration Number
- NCT00301210
- Locations
- 🇺🇸
Behavioral Pharmacology Research Unit, Baltimore, Maryland, United States
Tramadol to Reduce Opioid Withdrawal Symptoms
- Conditions
- First Posted Date
- 2005-09-02
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 16
- Registration Number
- NCT00142896
- Locations
- 🇺🇸
Johns Hopkins University (BPRU) Bayview Campus, Baltimore, Maryland, United States
Pain Relief - Tramadol Versus Ibuprofen
- Conditions
- First Posted Date
- 2005-05-17
- Last Posted Date
- 2005-11-10
- Lead Sponsor
- Royal Liverpool University Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT00111046
- Locations
- 🇬🇧
Royal Liverpool University Hospital, Liverpool, Merseyside, United Kingdom
Drug Development Updates
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