Celecoxib
- Generic Name
- Celecoxib
- Brand Names
- Celebrex, Elyxyb, Seglentis
- Drug Type
- Small Molecule
- Chemical Formula
- C17H14F3N3O2S
- CAS Number
- 169590-42-5
- Unique Ingredient Identifier
- JCX84Q7J1L
- Background
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon...
- Indication
Celecoxib is indicated for symptomatic treatment of adult osteoarthritis (OA) and adult rheumatoid arthritis (RA). Celecoxib is not a substitute for aspirin for cardiovascular event prophylaxis.
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- Associated Conditions
- Acute Pain, Ankylosing Spondylitis (AS), Osteoarthritis (OA), Primary Dysmenorrhoea, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Severe Acute Pain
- Associated Therapies
- -
Peri-Articular-Multimodal Drug and Oral Celecoxib in Management of Postoperative Pain of Total Knee Arthroplasty
- Conditions
- Interventions
- First Posted Date
- 2022-04-13
- Last Posted Date
- 2022-04-14
- Lead Sponsor
- Isfahan University of Medical Sciences
- Target Recruit Count
- 146
- Registration Number
- NCT05324995
- Locations
- 🇮🇷
Isfahan University of Medical Sciences, Isfahan, Iran, Islamic Republic of
Chidamide + Celecoxib in Advanced Metastatic Colorectal Cancer (CCmCC)
- First Posted Date
- 2022-03-16
- Last Posted Date
- 2024-12-20
- Lead Sponsor
- Taipei Medical University Shuang Ho Hospital
- Target Recruit Count
- 9
- Registration Number
- NCT05281276
- Locations
- 🇨🇳
Taipei Medical University Shuang Ho Hospital, New Taipei City, Taiwan
Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues on the Hepatitis B Surface Antigen of Virally Suppressed Subjects With Chronic Hepatitis B
- First Posted Date
- 2022-02-25
- Last Posted Date
- 2022-08-03
- Lead Sponsor
- Lai Wei
- Target Recruit Count
- 47
- Registration Number
- NCT05256823
- Locations
- 🇨🇳
Peking University People's Hospital, Beijing, Beijing, China
🇨🇳Bejing Tsinghua Changgung Hospital, Beijing, Bejing, China
🇨🇳Tianjin Third Center Hospital, Tianjin, Tianjin, China
Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Naproxen, Aceclofenac, Celecoxib and Ilaprazole
- Conditions
- Interventions
- First Posted Date
- 2022-02-14
- Last Posted Date
- 2023-06-28
- Lead Sponsor
- Il-Yang Pharm. Co., Ltd.
- Target Recruit Count
- 72
- Registration Number
- NCT05237297
- Locations
- 🇰🇷
Severance Hospital, Seoul, Korea, Republic of
Leidos-Enabled Adaptive Protocol for Clinical Trials (LEAP-CT) in Hospitalized Patients With COVID-19 (Addendum 1)
- Conditions
- Interventions
- First Posted Date
- 2021-10-20
- Last Posted Date
- 2023-10-10
- Lead Sponsor
- Leidos Life Sciences
- Registration Number
- NCT05085574
Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients
- First Posted Date
- 2021-10-14
- Last Posted Date
- 2024-07-09
- Lead Sponsor
- Leidos Life Sciences
- Target Recruit Count
- 4
- Registration Number
- NCT05077969
- Locations
- 🇺🇸
Integrated Therapeutic Solutions USA, Inc., Dallas, Texas, United States
🇺🇸Integrated Therapeutic Solutions USA, Inc, Dearborn, Michigan, United States
🇺🇸Integrated Health Solutions USA, Inc., Atlanta, Georgia, United States
LEAP-CT for Treatment of COVID-19 Patients (Master Protocol)
- Conditions
- Interventions
- First Posted Date
- 2021-10-14
- Last Posted Date
- 2023-10-10
- Lead Sponsor
- Leidos Life Sciences
- Target Recruit Count
- 2000
- Registration Number
- NCT05077332
- Locations
- 🇺🇸
US02-04: Integrated Health Solutions, Miami, Florida, United States
PET Imaging of Cyclooxygenase in Multiple Sclerosis
- Conditions
- Interventions
- First Posted Date
- 2021-09-30
- Last Posted Date
- 2024-06-27
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 7
- Registration Number
- NCT05062083
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Comparison of Postoperative Pain Management in Patients Undergoing Laparoscopic Colorectal Surgery Under Enhanced Recovery After Surgery (ERAS) Program, Laparoscopic Colorectal Surgery Without ERAS and Open Colorectal Surgery
- Conditions
- Interventions
- First Posted Date
- 2021-08-09
- Last Posted Date
- 2021-10-18
- Lead Sponsor
- Prince of Songkla University
- Target Recruit Count
- 162
- Registration Number
- NCT04997174
- Locations
- 🇹🇭
Sasikaan Nimmaanrat, Hat Yai, Songkhla, Thailand
Preemptive Analgesia With Celecoxib for Acute Dental Pain Management
- Conditions
- Interventions
- First Posted Date
- 2021-03-10
- Last Posted Date
- 2024-03-27
- Target Recruit Count
- 65
- Registration Number
- NCT04790812
- Locations
- 🇺🇸
The University of Texas Health Science Center at Houston, Houston, Texas, United States
Drug Development Updates
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