Sertraline

Generic Name
Sertraline
Brand Names
Zoloft
Drug Type
Small Molecule
Chemical Formula
C17H17Cl2N
CAS Number
79617-96-2
Unique Ingredient Identifier
QUC7NX6WMB
Background

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
...

Indication

Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety di...

Associated Conditions
Binge Eating Disorder (BED), Bulimia Nervosa, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD)
Associated Therapies
-
Clinical Trials
Related News

Combined Treatment for Alcohol-Dependent Individuals With PTSD

First Posted Date
2005-12-06
Last Posted Date
2020-03-03
Lead Sponsor
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Target Recruit Count
69
Registration Number
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Locations
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Treatment of Orthostatic Intolerance

First Posted Date
2005-12-06
Last Posted Date
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Registration Number
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Effectiveness of Sertraline in Treating Pathological Gamblers With a Diagnosis of Alcohol Dependence - 1

First Posted Date
2005-11-07
Last Posted Date
2017-10-27
Lead Sponsor
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Target Recruit Count
9
Registration Number
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Magnetic Resonance Imaging Study of Geriatric Depression

Not Applicable
Completed
Conditions
Major Depressive Disorder
Interventions
Drug: Sertraline
First Posted Date
2005-10-28
Last Posted Date
2017-03-30
Lead Sponsor
Mclean Hospital
Target Recruit Count
43
Registration Number
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Locations
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McLean Hospital, Belmont, Massachusetts, United States

Treatment of Post-Traumatic Brain Injury (TBI) Depression

Phase 2
Completed
Conditions
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Interventions
Drug: Sertraline
Drug: Placebo
First Posted Date
2005-10-05
Last Posted Date
2015-11-13
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
52
Registration Number
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Locations
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Icahn School of Medicine at Mount Sinai, New York, New York, United States

Treatment of Comorbid Depression and Substance Abuse in Young People

First Posted Date
2005-10-04
Last Posted Date
2015-06-26
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Target Recruit Count
60
Registration Number
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Locations
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Study Of Indiplon/Placebo With Sertraline In Insomnia Co-Existing With Depression

Phase 3
Terminated
Conditions
Insomnia
Depression
First Posted Date
2005-10-04
Last Posted Date
2007-10-02
Lead Sponsor
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Target Recruit Count
380
Registration Number
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Geodon for the Treatment of Refractory Social Anxiety Disorder

Phase 2
Completed
Conditions
Social Anxiety Disorder
Interventions
Drug: Ziprasidone
Drug: Sertraline
First Posted Date
2005-09-22
Last Posted Date
2014-10-31
Lead Sponsor
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First Posted Date
2005-09-21
Last Posted Date
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153
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Locations
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Sertraline vs. Placebo for Symptoms Following Traumatic Brain Injury

Not Applicable
Conditions
Traumatic Brain Injury
First Posted Date
2005-09-21
Last Posted Date
2007-10-10
Lead Sponsor
Walter Reed Army Medical Center
Target Recruit Count
100
Registration Number
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Locations
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Walter Reed Army Medical Center, Washington, District of Columbia, United States

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