Sugammadex
- Generic Name
- Sugammadex
- Brand Names
- Bridion, Sugammadex Adroiq, Sugammadex Amomed, Sugammadex Fresenius Kabi, Sugammadex Mylan, Sugammadex Piramal
- Drug Type
- Small Molecule
- Chemical Formula
- C72H112O48S8
- CAS Number
- 343306-71-8
- Unique Ingredient Identifier
- 361LPM2T56
- Background
Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intuba...
- Indication
Sugammadex is indicated for the reversal of neuromuscular blockade induced by rocuronium bromide or vecuronium bromide in adults and pediatric patients ≥2 years old who are undergoing surgery.
- Associated Conditions
- Neuromuscular blockade caused by vecuronium bromide
- Associated Therapies
- -
Sugammadex and Decreased Time to Extubation
- Conditions
- Interventions
- First Posted Date
- 2017-06-22
- Last Posted Date
- 2022-01-14
- Lead Sponsor
- Yale University
- Target Recruit Count
- 90
- Registration Number
- NCT03196167
- Locations
- 🇺🇸
Yale University, New Haven, Connecticut, United States
Sugammadex vs. Neostigmine for Neuromuscular Blockade Reversal in Thoracic Surgical Patients
- Conditions
- Interventions
- First Posted Date
- 2017-05-30
- Last Posted Date
- 2020-06-04
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 92
- Registration Number
- NCT03168308
- Locations
- 🇺🇸
Parkland Health & Hospital System, Dallas, Texas, United States
Investigation of Sugammadex in Outpatient Urological Procedures
- Conditions
- Interventions
- First Posted Date
- 2017-05-03
- Last Posted Date
- 2020-09-22
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 54
- Registration Number
- NCT03138967
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle Relaxant
- First Posted Date
- 2017-04-17
- Last Posted Date
- 2023-03-07
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 201
- Registration Number
- NCT03116997
- Locations
- 🇺🇸
Memoral Sloan Kettering Basking Ridge, Basking Ridge, New Jersey, United States
🇺🇸Memorial Sloan Kettering Commack, Commack, New York, United States
🇺🇸Memoral Sloan Kettering Westchester, Harrison, New York, United States
Speed of Recovery of Reversal of Neuromuscular Blockade in Geriatric Patients Undergoing Spine Surgery
- First Posted Date
- 2017-04-13
- Last Posted Date
- 2022-04-01
- Lead Sponsor
- University of Missouri-Columbia
- Target Recruit Count
- 40
- Registration Number
- NCT03112993
- Locations
- 🇺🇸
University on Missouri Hospital, Columbia, Missouri, United States
Use of Sugammadex for Reversal of Paralysis in Microlaryngoscopy
- Conditions
- Interventions
- First Posted Date
- 2017-04-12
- Last Posted Date
- 2019-04-29
- Lead Sponsor
- West Virginia University
- Target Recruit Count
- 84
- Registration Number
- NCT03111121
- Locations
- 🇺🇸
WVU Healthcare Ruby Memorial Hospital, Morgantown, West Virginia, United States
Comparison the Postoperative Quality of Recovery Between Neostigmine and Sugammadex in Elderly Patients Undergoing Trans Pars Plana Vitrectomy With General Anesthesia -Randomized Controlled Trial-
- Conditions
- Interventions
- First Posted Date
- 2017-04-11
- Last Posted Date
- 2017-11-17
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 90
- Registration Number
- NCT03108989
- Locations
- 🇰🇷
Department of Anesthesiology and Pain Medicine, Seoul, Korea, Republic of
Neuromuscular Blockade During Transurethral Resection of Bladder Cancer
- First Posted Date
- 2017-02-01
- Last Posted Date
- 2018-05-22
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 108
- Registration Number
- NCT03039543
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of
Deep Neuromuscular Block for Laparoscopic Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-01-27
- Last Posted Date
- 2020-04-22
- Lead Sponsor
- University of Melbourne
- Target Recruit Count
- 350
- Registration Number
- NCT03034577
- Locations
- 🇦🇺
Melbourne Health, Parkville, Victoria, Australia
🇦🇺Victorian Comprehensive Cancer Centre, Parkville, Victoria, Australia
🇦🇺The Royal Womens Hospital, Parkville, Victoria, Australia
Cerebral Oxygenation and Metabolism After Reversal Of Rocuronium: Comparison Between Sugammadex Versus Neostigmine
- Conditions
- Interventions
- First Posted Date
- 2016-10-25
- Last Posted Date
- 2018-10-19
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 40
- Registration Number
- NCT02944175
Drug Development Updates
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