Amoxicillin
- Generic Name
- Amoxicillin
- Brand Names
- Amoxil, Augmentin, Clavulin, Moxatag, Omeclamox, Prevpac, Talicia, Voquezna 14 Day Dualpak 20;500, Voquezna 14 Day Triplepak 20;500;500
- Drug Type
- Small Molecule
- Chemical Formula
- C16H19N3O5S
- CAS Number
- 26787-78-0
- Unique Ingredient Identifier
- 9EM05410Q9
- Background
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin.
Amoxicillin was granted FDA approval on 18 January 1974.
- Indication
Amoxicillin alone is indicated to treat susceptible bacterial infections of the ear, nose, throat, genitourinary tract, skin, skin structure, and lower respiratory tract. Amoxicillin is given with calvulanic acid to treat acute bacterial sinusitis, community acquired pneumonia, lower respiratory tract infections, acute bacterial otitis media, skin and skin s...
- Associated Conditions
- Acute Bacterial Sinusitis (ABS), Acute Otitis Media (AOM), Bacterial Infections, Community Acquired Pneumonia (CAP), Duodenal ulcer caused by helicobacter pylori, Genitourinary tract infection, Helicobacter Pylori Infection, Lower Respiratory Tract Infection (LRTI), Peptic Ulcer With H. Pylori Infection, Sinusitis, Skin and Subcutaneous Tissue Bacterial Infections, Urinary Tract Infection, Acute, uncomplicated Gonorrhea, Ear, nose, and throat infections
- Associated Therapies
- -
Banxiaxiexin Decoction Combined With Vonoprazan-Amoxicillin Dual Therapy in H.Pylori Eradication
- Conditions
- Interventions
- First Posted Date
- 2024-04-01
- Last Posted Date
- 2024-04-01
- Target Recruit Count
- 100
- Registration Number
- NCT06340724
- Locations
- 🇨🇳
Nanjing First Hospitai, Nanjing, Jiangsu, China
Effect of Gut Microbiota After High-dose Dual Therapy Combined With Probiotics for Helicobacter Pylori Eradication
- Conditions
- Interventions
- First Posted Date
- 2024-03-05
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Zhongshan Hospital (Xiamen), Fudan University
- Target Recruit Count
- 44
- Registration Number
- NCT06292546
- Locations
- 🇨🇳
Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian, China
Amoxicillin Alone Versus Amoxicillin/Clavulanate for Community-acquired Pneumonia in Patients Aged 65 Years or Older, and Hospitalized in a Non-intensive Care Unit Ward
- Conditions
- Interventions
- First Posted Date
- 2024-01-29
- Last Posted Date
- 2024-10-30
- Lead Sponsor
- Nantes University Hospital
- Target Recruit Count
- 326
- Registration Number
- NCT06229288
- Locations
- 🇫🇷
CHU Angers, Angers, France
🇫🇷Chu Angers, Angers, France
🇫🇷CHU Avicenne AP-HP, Bobigny, France
Feasibility Study of the Proposed Test-and-treat Screening Program in Younger Participants With H. Pylori Infection
- First Posted Date
- 2024-01-22
- Last Posted Date
- 2024-02-09
- Lead Sponsor
- National Institute of Public Health, Slovenia
- Target Recruit Count
- 2000
- Registration Number
- NCT06216639
- Locations
- 🇸🇮
Community Healthcare Center dr. Adolf Drolc Maribor (HCM), Maribor, Slovenia
Helicobacter Rescue Therapy With Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy
- First Posted Date
- 2023-12-13
- Last Posted Date
- 2024-07-30
- Lead Sponsor
- Yongquan Shi
- Target Recruit Count
- 688
- Registration Number
- NCT06168084
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xi'an, Shanxi, China
Vonoprazan for Helicobacter Pylori Eradication in Adolescents
- Conditions
- Interventions
- First Posted Date
- 2023-12-08
- Last Posted Date
- 2024-08-28
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 242
- Registration Number
- NCT06162949
- Locations
- 🇪🇬
Faculty of Medicine, Alexandria, Egypt
Choline to Improve Malnutrition and Enhance Cognition
- First Posted Date
- 2023-12-04
- Last Posted Date
- 2024-12-12
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 1500
- Registration Number
- NCT06154174
- Locations
- 🇲🇼
Makhwira, Makhwira, Chikwawa, Malawi
🇲🇼Chikonde, Chikonde, Mulanje, Malawi
🇲🇼Chipolonga, Chipolonga, Machinga, Malawi
Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice
- Conditions
- Interventions
- First Posted Date
- 2023-11-14
- Last Posted Date
- 2024-05-31
- Lead Sponsor
- Rutgers, The State University of New Jersey
- Target Recruit Count
- 544
- Registration Number
- NCT06131021
- Locations
- 🇺🇸
University of Alabame, Birmingham, Alabama, United States
Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: Short-course Therapy
- First Posted Date
- 2023-11-09
- Last Posted Date
- 2024-12-12
- Lead Sponsor
- Jeffrey
- Target Recruit Count
- 75
- Registration Number
- NCT06125340
- Locations
- 🇨🇦
McMaster Children's Hospital, Hamilton, Ontario, Canada
A Study to Evaluate Preliminary Helicobacter Pylori Eradication After Multiple Doses of TNP-2198 Capsules Combined With Rabeprazole Sodium Enteric-coated Tablets, or Rabeprazole Sodium Enteric-coated Tablets and Amoxicillin Capsules
- Conditions
- Interventions
- First Posted Date
- 2023-10-11
- Last Posted Date
- 2023-11-22
- Lead Sponsor
- TenNor Therapeutics (Suzhou) Limited
- Target Recruit Count
- 40
- Registration Number
- NCT06076681
- Locations
- 🇨🇳
The First Hospital of Jilin University, Chang chun, Jilin, China
Drug Development Updates
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