MedPath

Ropivacaine

Generic Name
Ropivacaine
Brand Names
Naropin
Drug Type
Small Molecule
Chemical Formula
C17H26N2O
CAS Number
84057-95-4
Unique Ingredient Identifier
7IO5LYA57N
Background

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.

Indication

Ropivacaine is indicated in adult patients for the induction of regional or local anesthesia for surgery or acute pain management.

Associated Conditions
Acute Pain, Postoperative pain
Associated Therapies
Surgical anesthesia therapy

Paravertebral Catheters for VATS Procedures

Early Phase 1
Completed
Conditions
Acute Pain
Interventions
Device: opioid iv pca
Device: Paravertebral catheter
Drug: Ropivacaine
Device: Elastomeric Pump
First Posted Date
2015-02-12
Last Posted Date
2015-02-12
Lead Sponsor
University of Minnesota
Target Recruit Count
50
Registration Number
NCT02361775

Adductor Canal Block Versus Femoral Nerve Block for Analgesia After Anterior Cruciate Ligament Reconstruction Arthroscopically

Phase 4
Conditions
Anesthesia; Reaction
Interventions
Procedure: adductor canal block (ACB)
Procedure: Femoral nerve block (FNB)
Drug: ropivacaine
First Posted Date
2015-02-04
Last Posted Date
2015-02-04
Lead Sponsor
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Target Recruit Count
40
Registration Number
NCT02355093

The T REX Pilot Study: a Study to Investigate the Use of an Alternative Anaesthetic in Infants.

Phase 4
Completed
Conditions
Surgical Procedures, Operative
Interventions
First Posted Date
2015-02-02
Last Posted Date
2016-10-26
Lead Sponsor
Murdoch Childrens Research Institute
Target Recruit Count
60
Registration Number
NCT02353182
Locations
🇺🇸

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States

🇺🇸

Texas Children's Hospital, Houston, Texas, United States

🇸🇬

KK Women's and Children's Hospital, Singapore, Singapore

and more 3 locations

Ultrasound-Guided Obturator Nerve Block for Ambulatory Hip Arthroscopy

Not Applicable
Conditions
Pain
Interventions
Procedure: Obturator Nerve Block
Drug: Ropivacaine
Drug: Placebo Saline
First Posted Date
2015-01-27
Last Posted Date
2015-01-27
Lead Sponsor
Benaroya Research Institute
Target Recruit Count
70
Registration Number
NCT02346357
Locations
🇺🇸

Virginia Mason Medical Center, Seattle, Washington, United States

Effect of Nervus Cutaneous Femoris Lateralis-Blockade on Moderate Pain Responders After Total Hip Arthroplasty

Phase 4
Completed
Conditions
Pain, Postoperative
Ropivacaine
Therapeutic Use
Arthroplasty, Replacement, Hip
Interventions
Drug: Ropivacaine
Drug: Saline
First Posted Date
2015-01-22
Last Posted Date
2015-09-25
Lead Sponsor
Daniel Hägi-Pedersen
Target Recruit Count
60
Registration Number
NCT02344264
Locations
🇩🇰

Department of Anaesthesiology, Næstved, Danmark, Denmark

Percutaneous Rectus Sheath Block Versus Intra-operative Rectus Sheath Block for Pediatric Umbilical Hernia Repair

Not Applicable
Completed
Conditions
Pain, Postoperative
Interventions
Procedure: Pre-op percutaneous rectus sheath block
Procedure: Intra-operative rectus sheath block
Drug: Ropivacaine
First Posted Date
2015-01-19
Last Posted Date
2023-07-03
Lead Sponsor
Johns Hopkins All Children's Hospital
Target Recruit Count
61
Registration Number
NCT02341144
Locations
🇺🇸

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida, United States

Single Shot Fascia Iliaca Block vs Femoral Nerve Block for Analgesia for Surgical Fixation of Hip Fractures

Not Applicable
Completed
Conditions
Hip Fracture
Interventions
First Posted Date
2015-01-01
Last Posted Date
2018-01-25
Lead Sponsor
Changi General Hospital
Target Recruit Count
30
Registration Number
NCT02330302
Locations
🇸🇬

Changi General Hospital, Singapore, Singapore

Influence of Epidural Analgesia on Natural Killer Cell (NK) Activity After Colonic Cancer Surgery

Not Applicable
Conditions
Colonic Neoplasms
Interventions
First Posted Date
2014-12-29
Last Posted Date
2014-12-29
Lead Sponsor
Hillel Yaffe Medical Center
Target Recruit Count
30
Registration Number
NCT02326727
Locations
🇮🇱

Hillel Yaffe Medical Center, Hadera, Israel

The Study of Ropivacaine Median Effective Concentration in Ultrasound-guided Supraclavicular Brachial Plexus Block

Phase 4
Conditions
Anesthesia
Interventions
First Posted Date
2014-12-23
Last Posted Date
2014-12-23
Lead Sponsor
Yu Shan
Target Recruit Count
60
Registration Number
NCT02323282
Locations
🇨🇳

Department of Anesthesiology,Sixth People's Hospital, Shanghai, Shanghai, China

Efficacy of Transversus Abdominis Plane Block Versus Local Injection of Pain Medication

Not Applicable
Completed
Conditions
Pain, Postoperative
Interventions
First Posted Date
2014-12-10
Last Posted Date
2015-04-14
Lead Sponsor
Liberman, Eric, D.O.
Target Recruit Count
220
Registration Number
NCT02314104
Locations
🇺🇸

Saint Barnabas Medical Center, Livingston, New Jersey, United States

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