Oxycodone

Generic Name
Oxycodone
Brand Names
Endocet, Endodan Reformulated May 2009, Nalocet, Oxaydo, Oxy.IR, Oxycontin, Oxyneo, Percocet, Prolate, Rivacocet, Roxicet, Roxicodone, Roxybond, Targin, Targiniq, Xolox, Xtampza
Drug Type
Small Molecule
Chemical Formula
C18H21NO4
CAS Number
76-42-6
Unique Ingredient Identifier
CD35PMG570
Background

Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period. The first oxycodone containing product, Percodan, wa...

Indication

Oxycodone is indicated for the treatment of moderate to severe pain. There is also an extended release formulation indicated for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.

Associated Conditions
Severe Acute Pain, Severe Pain, Severe, Chronic Pain, Acute, moderate Pain, Chronic, moderate Pain
Associated Therapies
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Clinical Evaluation of the ReLeaf Analgesic Infusion Catheter & Wound Drain

First Posted Date
2014-11-18
Last Posted Date
2016-01-22
Lead Sponsor
Vital 5, LLC
Registration Number
NCT02293525

A Study of the Abuse Liability Potential of Samidorphan in Healthy, Non-Dependent, Recreational Opioid Users

First Posted Date
2014-08-15
Last Posted Date
2014-12-02
Lead Sponsor
Alkermes, Inc.
Target Recruit Count
59
Registration Number
NCT02218021
Locations
🇺🇸

Alkermes Investigational Site, Overland Park, Kansas, United States

Effects of Ethanol on Oxycodone Pharmacokinetics in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-06-18
Last Posted Date
2016-04-04
Lead Sponsor
Pain Therapeutics
Target Recruit Count
17
Registration Number
NCT02165930
Locations
🇺🇸

Pfizer Investigational Site, Overland Park, Kansas, United States

Effect of a Multimodal Pain Regimen on Pain Control, Patient Satisfaction and Narcotic Use in Orthopaedic Trauma Patients

First Posted Date
2014-06-10
Last Posted Date
2017-05-19
Lead Sponsor
University of North Carolina, Chapel Hill
Registration Number
NCT02160301
Locations
🇺🇸

UNC Chapel Hill Hospital, Chapel Hill, North Carolina, United States

Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals

First Posted Date
2014-05-13
Last Posted Date
2014-05-13
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
12
Registration Number
NCT02136784
Locations
🇺🇸

UCLA Integrated Substance Abuse Programs Outpatient Clinical Research Center, Los Angeles, California, United States

Effects of Food on Oxycodone Pharmacokinetics in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-04-21
Last Posted Date
2016-04-04
Lead Sponsor
Pain Therapeutics
Target Recruit Count
34
Registration Number
NCT02117583
Locations
🇺🇸

Pfizer Investigational Site, Overland Park, Kansas, United States

Decreasing Narcotics in Advanced Pelvic Surgery

First Posted Date
2014-04-10
Last Posted Date
2016-08-17
Lead Sponsor
Hartford Hospital
Target Recruit Count
138
Registration Number
NCT02110719
Locations
🇺🇸

Hartford Hosptial, Hartford, Connecticut, United States

A Comparison of Targinact vs. Oxycodone on Gut Function After Colorectal Surgery

First Posted Date
2014-04-10
Last Posted Date
2017-03-29
Lead Sponsor
University of Edinburgh
Target Recruit Count
50
Registration Number
NCT02109640
Locations
🇬🇧

Western General Hospital, Edinburgh, United Kingdom

Dose Proportionality Study Of PF-00345439 Formulation Under Fed Conditions

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-03-17
Last Posted Date
2016-04-04
Lead Sponsor
Pain Therapeutics
Target Recruit Count
18
Registration Number
NCT02089295
Locations
🇺🇸

Pfizer Investigational Site, Overland Park, Kansas, United States

Single-Dose, Crossover Study To Compare Bioavailability Of Two Formulations Under Fed And Fasted Conditions

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-02-11
Last Posted Date
2016-04-04
Lead Sponsor
Pain Therapeutics
Target Recruit Count
134
Registration Number
NCT02059915
Locations
🇺🇸

Pfizer Investigational Site, St. Paul, Minnesota, United States

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