Duloxetine
- Generic Name
- Duloxetine
- Brand Names
- Cymbalta, Drizalma, Irenka, Yentreve, Duloxetine Zentiva, Duloxetine Mylan, Duloxetine Lilly
- Drug Type
- Small Molecule
- Chemical Formula
- C18H19NOS
- CAS Number
- 116539-59-4
- Unique Ingredient Identifier
- O5TNM5N07U
- Background
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor. It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a variety of indications including the tre...
- Indication
Indicated for:
1) Management of Major Depressive Disorder.
2) Management of Generalized Anxiety Disorder.
3) Management of diabetic peripheral neuropathy.
4) Management of fibromyalgia.
5) Management of chronic musculoskeletal pain.
6) Management of osteoarthritis of the knee in adults.
7) Management of chronic lower back pain in adults.
...
- Associated Conditions
- Chronic Lower Back Pain (CLBP), Chronic Musculoskeletal Pain, Diabetic Peripheral Neuropathic Pain (DPN), Fibromyalgia, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Osteoarthritis of the Knee, Stress Urinary Incontinence (SUI)
- Associated Therapies
- -
Capsaicin 179 mg Patch Versus Oral Duloxetine in Patients With Chemotherapy-induced Peripheral Neuropathy
- Conditions
- Interventions
- First Posted Date
- 2023-05-03
- Last Posted Date
- 2024-08-02
- Lead Sponsor
- Institut Cancerologie de l'Ouest
- Target Recruit Count
- 274
- Registration Number
- NCT05840562
- Locations
- 🇫🇷
Centre François Baclesse, Caen, France
🇫🇷CHU Grenoble, Grenoble, France
🇫🇷Centre Léon Bérard, Lyon, France
Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)
- Conditions
- Interventions
- First Posted Date
- 2023-04-18
- Last Posted Date
- 2023-08-14
- Target Recruit Count
- 520
- Registration Number
- NCT05814640
- Locations
- 🇨🇳
The First Affiliated Hospital of Chongqing Medical University, Chongqing, Province, China
Methadone to Treat Painful Chemotherapy Induced Peripheral Neuropathy
- Conditions
- Interventions
- First Posted Date
- 2023-03-27
- Last Posted Date
- 2024-02-14
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 50
- Registration Number
- NCT05786599
Therapeutic Efficacy in Women With Stress Urinary Incontinence
- Conditions
- Interventions
- First Posted Date
- 2023-01-10
- Last Posted Date
- 2023-05-19
- Lead Sponsor
- Far Eastern Memorial Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT05677295
- Locations
- 🇨🇳
Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, Banqiao, New Taipei, Taiwan
Qutenza Versus Duloxetine in Chemotherapy-induced Peripheral Neuropathy (CIPN)
- Conditions
- Interventions
- First Posted Date
- 2022-09-29
- Last Posted Date
- 2023-12-15
- Target Recruit Count
- 102
- Registration Number
- NCT05560516
- Locations
- 🇳🇱
Amsterdam UMC, locatie VUMC, Amsterdam, Netherlands
Duloxetine on Bone Metabolism
- First Posted Date
- 2022-09-22
- Last Posted Date
- 2022-09-22
- Lead Sponsor
- Cukurova University
- Target Recruit Count
- 102
- Registration Number
- NCT05550506
- Locations
- 🇹🇷
Çukurova Üniversitesi, Adana, Turkey
The BEST Trial: Biomarkers for Evaluating Spine Treatments
- Conditions
- Interventions
- First Posted Date
- 2022-05-27
- Last Posted Date
- 2024-10-11
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 1014
- Registration Number
- NCT05396014
- Locations
- 🇺🇸
Stanford University, Redwood City, California, United States
🇺🇸University of Washington, Seattle, Washington, United States
🇺🇸University of California, San Francisco, San Francisco, California, United States
Botulinum Toxin Type A in Diabetic Peripheral Neuropathy
- Conditions
- Interventions
- First Posted Date
- 2022-03-25
- Last Posted Date
- 2022-04-06
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 30
- Registration Number
- NCT05296759
- Locations
- 🇪🇬
faculty of medicine Alexandria university, Alexandria, Egypt
Duloxetine for Postoperative Pain of Laparoscopic Cholecystectomy
- First Posted Date
- 2021-11-10
- Last Posted Date
- 2022-05-16
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 60
- Registration Number
- NCT05115123
- Locations
- 🇪🇬
Mansoura University, Mansoura, Egypt
Duloxetine RCT on Postop TKA Outcomes
- Conditions
- Interventions
- First Posted Date
- 2021-10-20
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- Rush University Medical Center
- Target Recruit Count
- 504
- Registration Number
- NCT05086393
- Locations
- 🇺🇸
Rush University medical Center, Chicago, Illinois, United States
Drug Development Updates
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