Metronidazole

Generic Name: Metronidazole

Brand Names: Flagyl, Flagystatin, Likmez, Metrocream, Metrogel, Metrolotion, Nidagel, Noritate, Nuvessa, Pylera, Rosadan, Vandazole

Drug Type: Small Molecule

Chemical Formula: C_₆H_₉N_₃O_₃

CAS Number: 443-48-1

Unique Ingredient Identifier: 140QMO216E

Background: Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections. Metronidazole has been used as an antibiotic for several decades, with added antiparasitic properties that set it ...

Indication: Metronidazole is indicated for the treatment of confirmed trichomoniasis caused by Trichomonas vaginalis (except for in the first trimester of pregnancy) and the patient's sexual partners, bacterial vaginosis, certain types of amebiasis, and various anaerobic infections. The above anaerobic infections may occur on the skin and skin structures, the abdomen, t...

Associated Conditions: Abscess Brain, Abscess, Intra-Abdominal, Anaerobic Bacterial Infection, Bacterial Endocarditis, Bacterial Peritonitis, Bacterial Septicemia, Bacterial Vaginosis (BV), Balantidiasis, Bone and Joint Infections, Central Nervous System Bacterial Infections, Empyema, Endometritis, Endomyometritis, Facial Rosacea, Giardiasis, Gynecological Infection, Helicobacter Pylori Infection, Inflammatory Papule, Inflammatory pustules, Liver Abscess, Amebic, Lower respiratory tract infection bacterial, Lung Abscess, Meningitis, Mixed Vaginal Infections, Mixed Vaginal Infections caused by Trichomonas Vaginalis, candida albicans, Periodontitis, Pneumonia, Postoperative Infections, Pouchitis, Skin and skin structure infections, Tetanus, Trichomonas Vaginitis, Tubo-ovarian abscess, Vaginal Candidiasis, Vaginitis Trichomonal, Vulvovaginitis, Acute Intestinal amebiasis, Asymptomatic Trichomoniasis, Entamoeba histolytica, Hepatic abscess, Intra-abdominal bacterial infections, Post-surgical vaginal cuff infection, Refractory Sinusitis, Symptomatic Trichomoniasis

Associated Therapies: -

Clinical Trials

Bacterial Vaginosis Home Screening to Prevent STDs

Phase 3

Completed

Conditions: Bacterial Vaginosis

Interventions: Drug: Metronidazole

First Posted Date: 2008-04-28

Last Posted Date: 2020-02-18

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 1370

Registration Number: NCT00667368

Locations: 🇺🇸
University of North Carolina School of Medicine - Center for Infectious Diseases, Chapel Hill, North Carolina, United States
🇺🇸
Johns Hopkins Bayview Medical Center - Infectious Diseases, Baltimore, Maryland, United States
🇺🇸
San Francisco Department of Public Health - San Francisco City Clinic, San Francisco, California, United States

and more 4 locations

The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients

Phase 2

Conditions: HIV Infections
Diarrhea
Bacterial Vaginosis

Interventions: Dietary Supplement: Lactobacillus rhamnosus GR-1 + Lactobacillus reuteri RC-14
Dietary Supplement: Placebo
Drug: Metronidazole

First Posted Date: 2007-09-28

Last Posted Date: 2009-01-30

Lead Sponsor: National Institute for Medical Research, Tanzania

Target Recruit Count: 65

Registration Number: NCT00536848

Locations: 🇹🇿
Sekou-Toure Regional Hospital, Mwanza, Tanzania

Antimicrobial PK in Infants With Suspected or Confirmed Infection

Completed

Conditions: Infection

Interventions: Drug: Ampicillin
Drug: Metronidazole
Drug: Piperacillin/Tazobactam
Drug: Acyclovir
Drug: Amphotericin B
Drug: Ambisome
Drug: Anidulafungin
Drug: Caspofungin

First Posted Date: 2007-06-26

Last Posted Date: 2012-11-19

Lead Sponsor: Duke University

Target Recruit Count: 450

Registration Number: NCT00491426

Locations: 🇺🇸
Children's National Medical Center, Washington, District of Columbia, United States
🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States
🇺🇸
University of California at San Diego, La Jolla, California, United States

and more 3 locations

Asymptomatic Bacterial Vaginosis and Herpes Simplex Virus Type 2 (BV/HSV-2) Shedding Study

Phase 4

Completed

Conditions: Bacterial Vaginosis

Interventions: Drug: Metronidazole

First Posted Date: 2007-04-23

Last Posted Date: 2017-05-11

Lead Sponsor: University of Pittsburgh

Target Recruit Count: 12

Registration Number: NCT00464542

Locations: 🇺🇸
University of Pittsburgh, Pittsburgh, Pennsylvania, United States
🇺🇸
University of Pittsburgh, Magee Womens Hospital, Pittsburgh, Pennsylvania, United States

Malabsorption as a Cause of Iron Treatment Failure in Infants

Not Applicable

Completed

Conditions: Iron Deficiency
Malabsorption

First Posted Date: 2007-04-05

Last Posted Date: 2007-04-05

Lead Sponsor: HaEmek Medical Center, Israel

Target Recruit Count: 100

Registration Number: NCT00456729

Locations: 🇮🇱
Pediatric Hematology Unit and Pediatric Dpt B - HaEmek Medical Center, Afula, Israel

Metronidazole for Pulmonary Tuberculosis (South Korea)

Phase 2

Completed

Conditions: Tuberculosis
Multi-Drug Resistant Tuberculosis

Interventions: Drug: Metronidazole
Procedure: Blood Draw
Procedure: CT Scan
Procedure: PET Scan

First Posted Date: 2007-01-22

Last Posted Date: 2013-07-10

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 35

Registration Number: NCT00425113

Locations: 🇰🇷
National Masan Tuberculosis Hospital, Masan, Korea, Republic of
🇰🇷
Yonsei University College of Medicine, Seoul, Korea, Republic of

Study of Nitazoxanide in the Treatment of Clostridium Difficile Colitis

Phase 2

Completed

Conditions: Clostridium Difficile

First Posted Date: 2007-01-04

Last Posted Date: 2007-01-04

Lead Sponsor: Romark Laboratories L.C.

Target Recruit Count: 114

Registration Number: NCT00417872

Locations: 🇺🇸
WellStar Infectious Diseases, Marietta, Georgia, United States
🇺🇸
The Reading Hospital and Medical Center, West Reading, Pennsylvania, United States
🇺🇸
Remington-Davis, Inc., and Riverside Infection Consultants, Inc., Columbus, Ohio, United States

and more 4 locations