Dobutamine
- Generic Name
- Dobutamine
- Drug Type
- Small Molecule
- Chemical Formula
- C18H23NO3
- CAS Number
- 34368-04-2
- Unique Ingredient Identifier
- 3S12J47372
- Background
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
- Indication
Indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
- Associated Conditions
- Cardiac Decompensation, Coronary Artery Disease (CAD)
- Associated Therapies
- Intravenous inotropic therapy
CAPITAL DOREMI 2: Inotrope Versus Placebo Therapy for Cardiogenic Shock
- Conditions
- Shock, Cardiogenic
- Interventions
- First Posted Date
- 2022-03-04
- Last Posted Date
- 2025-04-10
- Lead Sponsor
- Ottawa Heart Institute Research Corporation
- Target Recruit Count
- 346
- Registration Number
- NCT05267886
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
🇨🇦Hamilton Health Sciences, Hamilton, Ontario, Canada
🇨🇦University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Supernormal Oxygen Delivery for Patients With Severe Burns
- First Posted Date
- 2022-02-16
- Last Posted Date
- 2022-02-16
- Lead Sponsor
- Guangzhou Red Cross Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT05241912
- Locations
- 🇨🇳
Guangzhou Red cross hospital, Guangzhou, Guangdong, China
Novel Echocardiographic and Invasive Haemodynamic Measurements in the Assessment of Patients Low Flow Low Gradient Aortic Stenosis Undergoing TAVI
- Conditions
- Cardiovascular Abnormalities
- Interventions
- First Posted Date
- 2022-01-19
- Last Posted Date
- 2025-01-06
- Lead Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
- Target Recruit Count
- 7
- Registration Number
- NCT05196815
- Locations
- 🇬🇧
The Royal Wolverhampton NHS Trust, Wolverhampton, West Midlands, United Kingdom
Quantitative Assessment of Hypertrophic Obstructive Cardiomyopathy With Intraoperative Three-dimensional Transesophageal Echocardiography Under Provocative Dobutamine Stress Test
- Conditions
- Hypertrophic Obstructive Cardiomyopathy
- First Posted Date
- 2021-08-27
- Last Posted Date
- 2022-11-08
- Lead Sponsor
- University Health Network, Toronto
- Target Recruit Count
- 60
- Registration Number
- NCT05025644
Effect of Dobutamine on Hepatic Blood Flow During Goal-directed Hemodynamic Therapy
- First Posted Date
- 2021-05-19
- Last Posted Date
- 2023-08-01
- Lead Sponsor
- University Hospital, Ghent
- Target Recruit Count
- 58
- Registration Number
- NCT04893655
- Locations
- 🇧🇪
Ghent University Hospital, Ghent, Belgium
Dobutamine on the Cardiac Conduction System
- First Posted Date
- 2020-01-30
- Last Posted Date
- 2022-01-26
- Lead Sponsor
- Northwell Health
- Target Recruit Count
- 37
- Registration Number
- NCT04249258
- Locations
- 🇺🇸
Long Island Jewish Hospital, New Hyde Park, New York, United States
Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion
- Conditions
- SepsisCardiomyopathiesHypoperfusionLeft Ventricular Systolic Dysfunction
- Interventions
- Drug: Placebos
- First Posted Date
- 2019-11-18
- Last Posted Date
- 2025-01-17
- Lead Sponsor
- University Hospital, Limoges
- Target Recruit Count
- 270
- Registration Number
- NCT04166331
- Locations
- 🇫🇷
University Hospital, Brest, France
🇫🇷Angouleme Hospital, Angoulême, France
🇫🇷Argenteuil Hospital, Argenteuil, France
Improving Tissue Oxygenation in Breast Reconstruction Surgery
- First Posted Date
- 2019-07-15
- Last Posted Date
- 2024-04-04
- Lead Sponsor
- Dr. Glenio Mizubuti (MD, MSc)
- Target Recruit Count
- 40
- Registration Number
- NCT04020172
- Locations
- 🇨🇦
Hotel Dieu Hospital, Kingston, Ontario, Canada
🇨🇦Kingston General Hospital, Kingston, Ontario, Canada
Influence of Continuous Administration of Phenylephrine Versus Dobutamine on Spinal Oxygen Saturation, Measured With Near-infrared Spectroscopy (NIRS).
- Conditions
- Nfuence of Vasoactive Medication on Spinal Oxygenation
- Interventions
- First Posted Date
- 2019-02-20
- Last Posted Date
- 2022-12-12
- Lead Sponsor
- University Hospital, Ghent
- Target Recruit Count
- 36
- Registration Number
- NCT03846765
- Locations
- 🇧🇪
Ghent University Hospital, Ghent, Belgium
Dobutamine in the Treatment of Haemodynamic Insufficiency in the Immediate Postnatal Period
- First Posted Date
- 2017-10-17
- Last Posted Date
- 2017-10-17
- Target Recruit Count
- 15
- Registration Number
- NCT03311178
- Locations
- 🇪🇸
La Paz University Hospital, Department of Neonatology, Madrid, Spain
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.