Dobutamine
- Generic Name
- Dobutamine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C18H23NO3
- CAS Number
- 34368-04-2
- Unique Ingredient Identifier
- 3S12J47372
- Background
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
- Indication
Indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
- Associated Conditions
- Cardiac Decompensation, Coronary Artery Disease (CAD)
- Associated Therapies
- Intravenous inotropic therapy
Dopamine Versus Dobutamine for Treatment of Arterial Hypotension in Term and Preterm Neonates
- First Posted Date
- 2011-09-01
- Last Posted Date
- 2016-04-06
- Lead Sponsor
- University of Ulm
- Target Recruit Count
- 20
- Registration Number
- NCT01427686
- Locations
- 🇩🇪
University Medical Center, Ulm University, Ulm, Baden-Württemberg, Germany
Assessment of the Effects of Pressors on Graft Blood Flow After Free Tissue Transfer Surgery
- Conditions
- Interventions
- First Posted Date
- 2011-08-16
- Last Posted Date
- 2011-08-16
- Lead Sponsor
- Oxford University Hospitals NHS Trust
- Target Recruit Count
- 25
- Registration Number
- NCT01418118
- Locations
- 🇬🇧
John Radcliffe Hospital, Oxford, Oxfordshire, United Kingdom
The Effects of Dobutamine on Postoperative Cardiac Function in Aortic Valve Replacement
- First Posted Date
- 2011-06-17
- Last Posted Date
- 2013-08-07
- Lead Sponsor
- University of Aarhus
- Target Recruit Count
- 10
- Registration Number
- NCT01375335
- Locations
- 🇩🇰
Department of Anaesthesia & Intensive Care, Århus University Hospital, Århus, Denmark
Reduced Contractile Reserve: a Therapeutic Target in Heart Failure With Preserved Ejection Fraction(HFpEF)
- Conditions
- Interventions
- First Posted Date
- 2011-05-17
- Last Posted Date
- 2019-04-11
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 14
- Registration Number
- NCT01354613
- Locations
- 🇺🇸
UW - Madison, Madison, Wisconsin, United States
Effects of Dobutamine on Microcirculation, Regional and Peripheral Perfusion in Septic Shock Patients
- First Posted Date
- 2011-01-06
- Last Posted Date
- 2015-06-26
- Lead Sponsor
- Pontificia Universidad Catolica de Chile
- Target Recruit Count
- 20
- Registration Number
- NCT01271153
- Locations
- 🇨🇱
Hospital Clinico Universidad Catolica de Chile, Santiago, RM, Chile
Effects of Levosimendan on Microcirculation in Septic Shock
- First Posted Date
- 2008-12-02
- Last Posted Date
- 2009-10-15
- Lead Sponsor
- University of Roma La Sapienza
- Target Recruit Count
- 40
- Registration Number
- NCT00800306
- Locations
- 🇮🇹
Departement of Anesthesiology and Intensive Care of the University of Rome "La Sapienza" Viale del Policlinico 155, Rome, Italy
Comparison of Dobutamine and Regadenoson Stress Cardiac Magnetic Resonance (MR)
- Conditions
- Interventions
- First Posted Date
- 2008-09-30
- Last Posted Date
- 2018-09-26
- Lead Sponsor
- Wake Forest University Health Sciences
- Target Recruit Count
- 14
- Registration Number
- NCT00763035
- Locations
- 🇺🇸
WAKE FOREST UNIVERSITY Baptist Medical Center, Winston-Salem, North Carolina, United States
Hemodynamics and Extravascular Lung Water in Acute Lung Injury
- Conditions
- Interventions
- First Posted Date
- 2008-02-27
- Last Posted Date
- 2019-09-10
- Lead Sponsor
- Oregon Health and Science University
- Target Recruit Count
- 33
- Registration Number
- NCT00624650
- Locations
- 🇺🇸
Legacy Good Samaritan, Portland, Oregon, United States
🇺🇸Oregon Health and Science University, Portland, Oregon, United States
🇺🇸Kaiser Permanente Sunnyside, Clackamas, Oregon, United States
Cardiac Function Under Stress for Early Detection of the Right Ventricular Insufficiency After Repair of Tetralogy of Fallot
- First Posted Date
- 2007-11-29
- Last Posted Date
- 2012-06-06
- Lead Sponsor
- Competence Network for Congenital Heart Defects
- Target Recruit Count
- 53
- Registration Number
- NCT00564993
- Locations
- 🇩🇪
Herzzentrum Leipzig, Klinik für Kinderkardiologie, Leipzig, Saxony, Germany
🇩🇪Herz-und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen, North Rhine-Westphalia, Germany
🇩🇪Deutsches Kinderherzzentrum St. Augustin, Sankt Augustin, North Rhine-Westphalia, Germany
Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsis
- Conditions
- First Posted Date
- 2007-06-08
- Last Posted Date
- 2008-01-22
- Lead Sponsor
- Onze Lieve Vrouwe Gasthuis
- Target Recruit Count
- 80
- Registration Number
- NCT00484133
- Locations
- 🇳🇱
Onze Lieve Vrouwe Gasthuis, intensive care, Amsterdam, Netherlands
Drug Development Updates
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