Dobutamine

Generic Name
Dobutamine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C18H23NO3
CAS Number
34368-04-2
Unique Ingredient Identifier
3S12J47372
Background

A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.

Indication

Indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.

Associated Conditions
Cardiac Decompensation, Coronary Artery Disease (CAD)
Associated Therapies
Intravenous inotropic therapy

Dobutamaine Versus Milrinone in Cardiorenal Syndrome

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2015-12-31
Last Posted Date
2018-08-10
Lead Sponsor
Maimonides Medical Center
Registration Number
NCT02644057
Locations
🇺🇸

Maimonides Medical Center, Brooklyn, New York, United States

Non-invasive Early Goal Directed Therapy in Colorectal Surgery: a Feasibility Study

First Posted Date
2015-09-24
Last Posted Date
2015-10-29
Lead Sponsor
University Hospital Schleswig-Holstein
Target Recruit Count
80
Registration Number
NCT02559141
Locations
🇩🇪

Ole Broch, Kiel, Schleswig-Holstein, Germany

Myocardial Regional Function by Dobutamine Stress Echocardiography in the Metabolic Syndrome and Type 2 Diabetes

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2015-07-22
Last Posted Date
2019-01-18
Lead Sponsor
University of Avignon
Target Recruit Count
125
Registration Number
NCT02505451
Locations
🇫🇷

Hospital Henri Duffaut, Avignon, Paca, France

Levosimendan Versus Dobutamine for Renal Function in Heart Failure

Phase 3
Completed
Conditions
Interventions
First Posted Date
2014-05-07
Last Posted Date
2020-02-25
Lead Sponsor
Göteborg University
Target Recruit Count
33
Registration Number
NCT02133105
Locations
🇸🇪

Sahlgrenska University Hospital, Gothenburg, Sweden

NeoAdapt 3: Novel Biomarkers in the Evaluation of Neonatal Circulatory Insufficiency in Babies Suffering From Hypoxic Ischemic Encephalopathy

Completed
Conditions
Interventions
First Posted Date
2014-01-31
Last Posted Date
2016-09-05
Lead Sponsor
Brighton and Sussex University Hospitals NHS Trust
Target Recruit Count
18
Registration Number
NCT02051894
Locations
🇬🇧

Trevor Mann Baby Unit, Brighton, Sussex, United Kingdom

Levosimendan Versus Dobutamine in Cardiopatic Patients Undergoing Major Non Cardiac Surgery

First Posted Date
2013-12-17
Last Posted Date
2013-12-17
Lead Sponsor
Azienda Policlinico Umberto I
Target Recruit Count
40
Registration Number
NCT02012946
Locations
🇮🇹

Francesco Pugliese, Rome, Italy

The Effects of Levosimendan During Mitral Valve Surgery

First Posted Date
2013-10-25
Last Posted Date
2013-10-25
Lead Sponsor
Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Target Recruit Count
140
Registration Number
NCT01969071
Locations
🇹🇷

Kartal Kosuyolu High Speciality Training and Research Hospital, Istanbul, Turkey

Outcome and Safety of Intermittent Dobutamine Infusion at a Day-Care Center in Advanced Heart Failure Patients

First Posted Date
2013-08-29
Last Posted Date
2013-08-30
Lead Sponsor
Sheba Medical Center
Target Recruit Count
60
Registration Number
NCT01930734
Locations
🇮🇱

Leviev Heart Center, Chaim Sheba Medical Center, Ramat-Gan, Israel

Dobutamine Versus Placebo for Low Superior Vena Cava Flow in Newborns

Phase 2
Completed
Conditions
Interventions
First Posted Date
2012-05-24
Last Posted Date
2015-03-09
Lead Sponsor
Adelina Pellicer
Target Recruit Count
127
Registration Number
NCT01605279
Locations
🇪🇸

La Paz University Hospital, Madrid, Spain

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