Dobutamine

Generic Name
Dobutamine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C18H23NO3
CAS Number
34368-04-2
Unique Ingredient Identifier
3S12J47372
Background

A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.

Indication

Indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.

Associated Conditions
Cardiac Decompensation, Coronary Artery Disease (CAD)
Associated Therapies
Intravenous inotropic therapy

Survival of Patients With Acute Heart Failure in Need of Intravenous Inotropic Support: a Multicentre, Parallel-Group, Randomised, Double-Blind, Double-Dummy Study of Levosimendan Versus Dobutamine in Patients With Acute Heart Failure.

Phase 3
Completed
Conditions
First Posted Date
2006-07-04
Last Posted Date
2007-11-20
Lead Sponsor
Abbott
Target Recruit Count
1300
Registration Number
NCT00348504
Locations
🇺🇸

Global Medical Information - Abbott, Abbott Park, Illinois, United States

Intravenous Allopurinol to Improve Heart Function in Individuals With Dilated Cardiomyopathy

First Posted Date
2006-01-24
Last Posted Date
2013-06-19
Lead Sponsor
University of Pennsylvania
Registration Number
NCT00281255
Locations
🇺🇸

University of Pennsylvania, Philadelphia, Pennsylvania, United States

DOCICAR: Cardiac Dysfunction in Cirrhosis

First Posted Date
2005-11-08
Last Posted Date
2007-11-01
Lead Sponsor
Hvidovre University Hospital
Registration Number
NCT00250315
Locations
🇩🇰

Hvidovre University Hospital, Copenhagen, Hvidovre, Denmark

Levosimendan Versus Dobutamine in Shock Patients

First Posted Date
2004-10-07
Last Posted Date
2005-06-24
Lead Sponsor
Wentworth Area Health Services
Target Recruit Count
40
Registration Number
NCT00093301
Locations
🇦🇺

Intensive Care Unit, Nepean Hospital, Penrith, New South Wales, Australia

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