Rifabutin
- Generic Name
- Rifabutin
- Brand Names
- Mycobutin, Talicia
- Drug Type
- Small Molecule
- Chemical Formula
- C46H62N4O11
- CAS Number
- 72559-06-9
- Unique Ingredient Identifier
- 1W306TDA6S
- Background
A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
- Indication
For the prevention of disseminated Mycobacterium avium complex (MAC) disease in patients with advanced HIV infection.
- Associated Conditions
- Helicobacter Pylori Infection, Mycobacterium avium complex infection, Tuberculosis (TB), Late phase Tuberculosis
- Associated Therapies
- -
Efficacy of a 14-Day Bismuth-Containing Quadruple Therapy Guided by Drug Susceptibility Testing in Patients with Extremely Refractory Helicobacter Pylori Infection: an Exploratory Study
- Conditions
- Interventions
- First Posted Date
- 2024-12-12
- Last Posted Date
- 2024-12-19
- Lead Sponsor
- Xiuli Zuo
- Target Recruit Count
- 30
- Registration Number
- NCT06731023
- Locations
- 🇨🇳
Qilu Hospital of Shandong University, Jinan, Shandong, China
Rescue Therapy for Helicobacter Pylori Infection
- Conditions
- Interventions
- First Posted Date
- 2023-05-25
- Last Posted Date
- 2024-10-22
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 357
- Registration Number
- NCT05874544
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
🇨🇳Shanghai Songjiang District Central Hospital, Shanghai, Shanghai, China
🇨🇳The Second Affiliated Hospital of Zhejiang University school of Medicine, Hangzhou, Zhejiang, China
Short-course Regimens for the Treatment of Pulmonary Tuberculosis
- First Posted Date
- 2023-03-13
- Last Posted Date
- 2024-01-08
- Lead Sponsor
- Centers for Disease Control and Prevention
- Target Recruit Count
- 288
- Registration Number
- NCT05766267
- Locations
- 🇺🇸
TBTC Site 26 Seattle & King County TB Control Program, Seattle, Washington, United States
🇺🇸TBTC Site 64A New York City Department of Health and Mental Hygiene- Corona Chest Center, Jackson Heights, New York, United States
🇺🇸TBTC Site 63 San Antonio VA Medical Center (South Texas Group), San Antonio, Texas, United States
Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels
- Conditions
- Interventions
- First Posted Date
- 2022-07-14
- Last Posted Date
- 2024-12-03
- Lead Sponsor
- Gilead Sciences
- Target Recruit Count
- 18
- Registration Number
- NCT05458102
- Locations
- 🇺🇸
Clinical Pharmacology of Miami, LLC., Miami, Florida, United States
🇺🇸Collaborative Neuroscience Research, LLC., Long Beach, California, United States
🇺🇸Triple O Research Institute, P.A., West Palm Beach, Florida, United States
Rifabutin Versus Rifampicin for Treatment of Staphylococcal PJI Treated With DAIR
- First Posted Date
- 2020-12-17
- Last Posted Date
- 2022-05-10
- Lead Sponsor
- Tourcoing Hospital
- Target Recruit Count
- 436
- Registration Number
- NCT04672525
- Locations
- 🇫🇷
CHU Reims, Reims, France
🇫🇷CH Annecy Genevois, Pringy, France
🇫🇷Clinique de la Sauvegarde, Lyon, France
Effectiveness of Rifabutin for Treatment of Helicobacter Pylori
- First Posted Date
- 2020-12-03
- Last Posted Date
- 2021-03-10
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 300
- Registration Number
- NCT04652284
A Study of Bedaquiline Administered as Part of a Treatment Regimen With Clarithromycin and Ethambutol in Adult Patients With Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)
- Conditions
- Interventions
- First Posted Date
- 2020-11-16
- Last Posted Date
- 2024-12-10
- Lead Sponsor
- Janssen Pharmaceutical K.K.
- Target Recruit Count
- 129
- Registration Number
- NCT04630145
- Locations
- 🇰🇷
Chonnam National University Hospital, Gwangju, Korea, Republic of
🇯🇵St. Luke's International Hospital, Chuo ku, Japan
🇯🇵Fukui Prefectural Hospital, Fukui-shi, Japan
The Effect of Moderate CYP3A Inducer Rifabutin on the Pharmacokinetics of Zanubrutinib in Healthy Males
- First Posted Date
- 2020-07-14
- Last Posted Date
- 2024-10-26
- Lead Sponsor
- BeiGene
- Target Recruit Count
- 13
- Registration Number
- NCT04470908
- Locations
- 🇺🇸
Covance Clinical Research Unit, Daytona Beach, Florida, United States
Finding the Optimal Regimen for Mycobacterium Abscessus Treatment
- Conditions
- Interventions
- First Posted Date
- 2020-03-17
- Last Posted Date
- 2024-12-11
- Lead Sponsor
- The University of Queensland
- Target Recruit Count
- 300
- Registration Number
- NCT04310930
- Locations
- 🇦🇺
St George Hospital, Kogarah, New South Wales, Australia
🇦🇺Austin Hospital, Heidelberg, Victoria, Australia
🇦🇺Royal Melbourne Hospital, Parkville, Victoria, Australia
A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and Rifabutin
- First Posted Date
- 2019-03-27
- Last Posted Date
- 2023-10-23
- Target Recruit Count
- 24
- Registration Number
- NCT03891901
- Locations
- 🇺🇸
Emory University DAIDS TB Non-Network CRS, Atlanta, Georgia, United States
Drug Development Updates
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