Indomethacin
- Generic Name
- Indomethacin
- Brand Names
- Indocin, Tivorbex
- Drug Type
- Small Molecule
- Chemical Formula
- C19H16ClNO4
- CAS Number
- 53-86-1
- Unique Ingredient Identifier
- XXE1CET956
- Background
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-ace...
- Indication
Oral indometacin is indicated for symptomatic management of moderate to severe rheumatoid arthritis including acute flares of chronic disease, moderate to severe ankylosing spondylitis, moderate to severe osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.
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- Associated Conditions
- Acute Gouty Arthritis, Joint Pain, Moderate to Severe Osteoarthritis, Moderate to Severe Rheumatoid Arthritis, Moderate to severe ankylosing spondylitis, Myalgia, Patent Ductus Arteriosus (PDA), Acute Shoulder Pain
- Associated Therapies
- -
Tocolysis for Preterm Labor
- Conditions
- Interventions
- First Posted Date
- 2008-12-18
- Last Posted Date
- 2013-04-04
- Lead Sponsor
- University of Mississippi Medical Center
- Target Recruit Count
- 301
- Registration Number
- NCT00811057
- Locations
- 🇺🇸
The Winfred L. Wiser Hospital for Women and Infants at the University of Mississippi Medical Center, Jackson, Mississippi, United States
An Escalating Dose Indomethacin for the Treatment of Persistent Patent Ductus Arteriosus (PDA) In Preterm Infants
- First Posted Date
- 2008-09-10
- Last Posted Date
- 2016-08-18
- Lead Sponsor
- University of Calgary
- Target Recruit Count
- 9
- Registration Number
- NCT00750581
- Locations
- 🇨🇦
Foothills Medical Centre, Calgary, Alberta, Canada
A Double-blind Study to Determine if Intraduodenal Indomethacin Can Decrease the Incidence of Post-ERCP Pancreatitis
- Conditions
- Interventions
- First Posted Date
- 2008-08-04
- Last Posted Date
- 2017-01-18
- Lead Sponsor
- Yale University
- Target Recruit Count
- 117
- Registration Number
- NCT00727740
- Locations
- 🇺🇸
Yale New Haven Hospital, New Haven, Connecticut, United States
Treating the Resistant Patent Ductus Arteriosus (PDA)
- First Posted Date
- 2008-02-15
- Last Posted Date
- 2008-02-15
- Lead Sponsor
- Shaare Zedek Medical Center
- Target Recruit Count
- 68
- Registration Number
- NCT00616382
- Locations
- 🇮🇱
Neonatal Intensive Care Unit - Shaare Zedek Medical Center, Jerusalem, Israel
Celebrex In Acute Gouty Arthritis Study
- First Posted Date
- 2007-10-26
- Last Posted Date
- 2021-02-21
- Target Recruit Count
- 402
- Registration Number
- NCT00549549
- Locations
- 🇹🇭
Pfizer Investigational Site, Khon Kaen, Thailand
Indomethacin Versus Nifedipine for Preterm Labor Tocolysis
- First Posted Date
- 2007-06-15
- Last Posted Date
- 2018-10-01
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 29
- Registration Number
- NCT00486824
- Locations
- 🇺🇸
Stanford University School of Medicine, Stanford, California, United States
Pharmacologic Treatment of Congenital Nephrogenic Diabetes Insipidus
- Conditions
- Interventions
- First Posted Date
- 2007-05-24
- Last Posted Date
- 2018-02-12
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 4
- Registration Number
- NCT00478335
- Locations
- 🇺🇸
University of Colorado at Denver and Health Sciences Center, Aurora, Colorado, United States
🇩🇰University of Aarhus, Aarhus, Denmark
Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus in Very Premature Babies
- Conditions
- Interventions
- First Posted Date
- 2007-05-08
- Last Posted Date
- 2015-09-02
- Lead Sponsor
- KK Women's and Children's Hospital
- Registration Number
- NCT00470743
- Locations
- 🇸🇬
KK Women's and Children's Hospital / National University Hospital, Singapore, Singapore
Indomethacin Versus Placebo in Women With Preterm Premature Rupture of Membranes (PPROM)
- Conditions
- First Posted Date
- 2007-04-27
- Last Posted Date
- 2015-03-18
- Lead Sponsor
- Thomas Jefferson University
- Target Recruit Count
- 116
- Registration Number
- NCT00466128
- Locations
- 🇺🇸
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States
Indomethacin and Mechanisms Underlying Risk of Falling
- Conditions
- First Posted Date
- 2007-04-18
- Last Posted Date
- 2012-02-14
- Lead Sponsor
- Sint Maartenskliniek
- Target Recruit Count
- 20
- Registration Number
- NCT00462111
- Locations
- 🇳🇱
Sint Maartenskliniek, Nijmegen, Netherlands
Drug Development Updates
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