Indomethacin
- Generic Name
- Indomethacin
- Brand Names
- Indocin, Tivorbex
- Drug Type
- Small Molecule
- Chemical Formula
- C19H16ClNO4
- CAS Number
- 53-86-1
- Unique Ingredient Identifier
- XXE1CET956
- Background
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-ace...
- Indication
Oral indometacin is indicated for symptomatic management of moderate to severe rheumatoid arthritis including acute flares of chronic disease, moderate to severe ankylosing spondylitis, moderate to severe osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.
...
- Associated Conditions
- Acute Gouty Arthritis, Joint Pain, Moderate to Severe Osteoarthritis, Moderate to Severe Rheumatoid Arthritis, Moderate to severe ankylosing spondylitis, Myalgia, Patent Ductus Arteriosus (PDA), Acute Shoulder Pain
- Associated Therapies
- -
Study of Indomethacin Capsules to Treat Pain Following Bunionectomy
- Conditions
- Interventions
- First Posted Date
- 2012-03-05
- Last Posted Date
- 2014-02-04
- Lead Sponsor
- Iroko Pharmaceuticals, LLC
- Target Recruit Count
- 462
- Registration Number
- NCT01543685
- Locations
- 🇺🇸
Chesapeake Research Group, LLC, Pasadena, Maryland, United States
🇺🇸Premier Research Group Limited, Salt Lake City, Utah, United States
Influence of Treatment for Patent Ductus Arteriosus on Cerebral Oxygenation in Preterm Infants
- Conditions
- Interventions
- First Posted Date
- 2011-09-02
- Last Posted Date
- 2016-04-06
- Lead Sponsor
- University of Ulm
- Target Recruit Count
- 35
- Registration Number
- NCT01428180
- Locations
- 🇩🇪
University Medical Center, Ulm, Baden-Württemberg, Germany
Nifedipine Versus Indomethacin in the Treatment of Preterm Labour
- First Posted Date
- 2011-05-25
- Last Posted Date
- 2015-01-05
- Lead Sponsor
- Saint Thomas Hospital, Panama
- Target Recruit Count
- 216
- Registration Number
- NCT01360034
- Locations
- 🇵🇦
Saint Thomas Hospital, Panama, Panama
Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
- Conditions
- First Posted Date
- 2011-01-20
- Last Posted Date
- 2011-12-05
- Lead Sponsor
- University of Calgary
- Target Recruit Count
- 12
- Registration Number
- NCT01280006
- Locations
- 🇨🇦
The Laboratory of Human Cerebrovascular Physiology, HMRB 209 & HMRB 230, University of Calgary, Calgary, Alberta, Canada
Efficacy and Safety Study of Leukocyte Interleukin,Injection (LI) to Treat Cancer of the Oral Cavity
- First Posted Date
- 2010-12-23
- Last Posted Date
- 2022-08-19
- Lead Sponsor
- CEL-SCI Corporation
- Target Recruit Count
- 928
- Registration Number
- NCT01265849
- Locations
- 🇨🇳
Linkou Branch Chang Gung Memorial Hospital, Guishan, Taoyuan, Taiwan
🇮🇳Meenakshi Mission Hospital and Research Centre, Madurai, Tamil Nadu, India
🇨🇦St. Josephs Healthcare Department of Surgery, Hamilton, Ontario, Canada
Indomethacin and Cardiac Bypass Surgery
- Conditions
- Interventions
- First Posted Date
- 2010-02-23
- Last Posted Date
- 2010-02-23
- Lead Sponsor
- Queen's University
- Target Recruit Count
- 82
- Registration Number
- NCT01073670
- Locations
- 🇨🇦
Kingston General Hospital, Kingston, Ontario, Canada
Second Course of Therapy for Resistant Patent Ductus Arteriosus (PDA)
- First Posted Date
- 2010-02-18
- Last Posted Date
- 2012-06-07
- Lead Sponsor
- Shaare Zedek Medical Center
- Registration Number
- NCT01070745
- Locations
- 🇮🇱
Shaare Zedek Medical Center, Jerusalem, Israel
Validation of New Tests for Gastrointestinal (GI) Permeability
- First Posted Date
- 2009-07-22
- Last Posted Date
- 2011-11-08
- Lead Sponsor
- Maastricht University Medical Center
- Target Recruit Count
- 34
- Registration Number
- NCT00943345
- Locations
- 🇳🇱
Maastricht University Medical Center, Maastricht, Zuid-Limburg, Netherlands
Study Utilizing Rilonacept in Gout Exacerbations
- Conditions
- Interventions
- First Posted Date
- 2009-03-05
- Last Posted Date
- 2017-04-28
- Lead Sponsor
- Regeneron Pharmaceuticals
- Target Recruit Count
- 225
- Registration Number
- NCT00855920
Rectal Indomethacin in the Prevention of Post-endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis in High Risk Patients
- Conditions
- Interventions
- First Posted Date
- 2009-01-12
- Last Posted Date
- 2013-02-28
- Lead Sponsor
- University of Michigan
- Target Recruit Count
- 602
- Registration Number
- NCT00820612
- Locations
- 🇺🇸
University of Kentucky, Lexington, Kentucky, United States
🇺🇸Indiana University Medical Center, Indianapolis, Indiana, United States
🇺🇸University Hospitals Case Medical Center, Cleveland, Ohio, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.