Chloroquine
- Generic Name
- Chloroquine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C18H26ClN3
- CAS Number
- 54-05-7
- Unique Ingredient Identifier
- 886U3H6UFF
- Background
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a number of other c...
- Indication
Chloroquine is indicated to treat infections of P. vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also used to treat extraintestinal amebiasis.
...
- Associated Conditions
- Discoid Lupus Erythematosus (DLE), Extraintestinal Amebiasis, Malaria, Polymorphic Light Eruption (PLE), Porphyria Cutanea Tarda, Rheumatoid Arthritis, Sarcoidosis, Acute, uncomplicated Malaria
- Associated Therapies
- -
A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid Arthritis
- Conditions
- Interventions
- First Posted Date
- 2013-09-13
- Last Posted Date
- 2018-11-13
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 100
- Registration Number
- NCT01941095
- Locations
- 🇬🇷
Laiko General Hospital; Dept. of Pathophysiology-Uni of Athens, Athens, Greece
🇬🇷Uni Hospital of Ioannina; Rheumatology, Ioannina, Greece
🇬🇷General Hospital of Thessaloniki HIPPOKRATIO; Clinical Immunology Unit,2nd Dept of Internal Medicine, Thessaloniki, Greece
Study of Whole-brain Irradiation With Chloroquine for Brain Metastases
- Conditions
- Interventions
- First Posted Date
- 2013-07-10
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Instituto Nacional de Cancerologia de Mexico
- Target Recruit Count
- 73
- Registration Number
- NCT01894633
- Locations
- 🇲🇽
Instituto Nacional de Cancerologia, Mexico DF, DF, Mexico
Antimalarial Drug Susceptibility and Molecular Characterization of Plasmodium Vivax Isolates in Vietnam
- Conditions
- Interventions
- First Posted Date
- 2013-06-27
- Last Posted Date
- 2016-09-30
- Target Recruit Count
- 330
- Registration Number
- NCT01887821
- Locations
- 🇻🇳
Bu Gia Map Health Station, Bu Gia Map, Binh Phuoc, Vietnam
Prednisone Plus Chloroquine for the Treatment of Hyper-reactive Malarial Splenomegaly
- Conditions
- Interventions
- First Posted Date
- 2013-02-07
- Last Posted Date
- 2015-11-13
- Lead Sponsor
- Lihir Medical Centre
- Registration Number
- NCT01785979
- Locations
- 🇵🇬
Lihir medical Centre, Londolovit, New ireland province, Papua New Guinea
Adjuvant Effect of Chloroquine on Gemcitabine
- First Posted Date
- 2013-01-28
- Last Posted Date
- 2015-09-22
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 9
- Registration Number
- NCT01777477
- Locations
- 🇨🇭
University Hospital Zurich, Department of Oncology, Zurich, ZH, Switzerland
Vascular Function Intervention Trial in Sickle Cell Disease
- First Posted Date
- 2012-10-31
- Last Posted Date
- 2016-07-27
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 120
- Registration Number
- NCT01718054
- Locations
- 🇹🇿
Muhimbili University of Heath and Allied Sciences (MUHAS), Dar es Salaam, Tanzania
Safety and Efficacy of Chloroquine and Primaquine for Vivax Malaria in Bhutan
- First Posted Date
- 2012-10-29
- Last Posted Date
- 2016-05-27
- Lead Sponsor
- Menzies School of Health Research
- Target Recruit Count
- 24
- Registration Number
- NCT01716260
- Locations
- 🇧🇹
Vector Diseases Control Program, Gelephu, Bhutan
P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine
- Conditions
- Interventions
- First Posted Date
- 2012-10-17
- Last Posted Date
- 2015-04-09
- Lead Sponsor
- Menzies School of Health Research
- Target Recruit Count
- 250
- Registration Number
- NCT01708876
- Locations
- 🇲🇾
Kudat District Hospital, Kudat, Sabah, Malaysia
🇲🇾Kota Marudu District Hospital, Kota Marudu, Sabah, Malaysia
🇲🇾Pitas District Hospital, Pitas, Sabah, Malaysia
Ethiopia Antimalarial in Vivo Efficacy Study 2012
- Conditions
- Interventions
- First Posted Date
- 2012-09-07
- Last Posted Date
- 2017-01-19
- Lead Sponsor
- Centers for Disease Control and Prevention
- Target Recruit Count
- 398
- Registration Number
- NCT01680406
- Locations
- 🇪🇹
Bishoftu Malaria Center, Debre Zeit, Ethiopia
🇪🇹Batu Health Center, Zeway, Ethiopia
Comparison of Two Antimalarial Drugs Regimens in Patient With Plasmodium Vivax Malaria in Thailand
- Conditions
- Interventions
- First Posted Date
- 2012-08-10
- Last Posted Date
- 2013-01-25
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 120
- Registration Number
- NCT01662700
- Locations
- 🇹🇭
Kraburi Hospital, Ranong, Thailand
🇹🇭Khunhan Hospital, Srisaket, Thailand
🇹🇭Kap Choeng Hospital, Surin, Thailand
Drug Development Updates
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