Bupivacaine

Generic Name
Bupivacaine
Brand Names
Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
Drug Type
Small Molecule
Chemical Formula
C18H28N2O
CAS Number
38396-39-3
Unique Ingredient Identifier
Y8335394RO
Background

Bupivacaine is a widely used local anesthetic agent.

Indication

As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
...

Associated Conditions
Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
Associated Therapies
General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy

EXPAREL Infiltrated Into the TAP for Postoperative Analgesia in Unilateral Abdominal Hernia Repair

Phase 4
Completed
Conditions
Interventions
First Posted Date
2013-02-28
Last Posted Date
2021-03-08
Lead Sponsor
Pacira Pharmaceuticals, Inc
Target Recruit Count
13
Registration Number
NCT01801124
Locations
🇺🇸

Maimonides Medical Center, Brooklyn, New York, United States

Dexamethasone and Block Duration in Upper Extremity

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2012-12-27
Last Posted Date
2019-05-14
Lead Sponsor
University of Chicago
Target Recruit Count
5
Registration Number
NCT01756573
Locations
🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

Dexamethasone and Lower Extremity Block Duration

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2012-12-27
Last Posted Date
2017-06-27
Lead Sponsor
University of Chicago
Target Recruit Count
4
Registration Number
NCT01756586
Locations
🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

Effect of Dexamethasone on Duration of Lower Extremity Blocks With Bupivacaine in Subjects Having ACL Repair

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2012-12-27
Last Posted Date
2019-05-14
Lead Sponsor
University of Chicago
Target Recruit Count
2
Registration Number
NCT01756560
Locations
🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

Bupivacaine Versus Lidocaine Local Anesthesia

First Posted Date
2012-12-18
Last Posted Date
2015-12-14
Lead Sponsor
University of British Columbia
Target Recruit Count
135
Registration Number
NCT01751347
Locations
🇨🇦

Vancouver General Hospital, Vancouver, British Columbia, Canada

Evaluation of a TAP Block Given During Laparoscopic Colorectal Surgery to Help Control Pain

First Posted Date
2012-11-22
Last Posted Date
2022-11-03
Lead Sponsor
University Hospitals Cleveland Medical Center
Target Recruit Count
79
Registration Number
NCT01731782
Locations
🇺🇸

University Hospitals Case Medical Center, Cleveland, Ohio, United States

Use of the Tx360 Nasal Applicator in the Treatment of Chronic Migraine

Phase 4
Completed
Conditions
Interventions
First Posted Date
2012-10-18
Last Posted Date
2018-01-26
Lead Sponsor
Tian Medical Inc.
Target Recruit Count
41
Registration Number
NCT01709708
Locations
🇺🇸

Clinvest/A Division of Banyan Group, Inc., Springfield, Missouri, United States

🇺🇸

Michigan Head Pain & Neurological Institute, Ann Arbor, Michigan, United States

Injection of Local Anesthetic to Trocar Insertion Sites After Laparoscopy

Phase 1
Completed
Conditions
Interventions
First Posted Date
2012-09-20
Last Posted Date
2019-09-09
Lead Sponsor
Milton S. Hershey Medical Center
Target Recruit Count
135
Registration Number
NCT01688596
Locations
🇺🇸

Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States

Comparison Between Ultrasound-guided and Landmark-guided Ankle Blocks

Conditions
Interventions
First Posted Date
2012-09-13
Last Posted Date
2012-09-13
Lead Sponsor
Hillel Yaffe Medical Center
Target Recruit Count
100
Registration Number
NCT01684774
Locations
🇮🇱

Hillel Yaffe Medical Center, Hadera, Israel

© Copyright 2024. All Rights Reserved by MedPath